Silica Resins
Description
Sepax manufactures wide range of silica based media with the particle size selection of 5, 10, 15, 20,
30, 50 and 60 µm spherical particles with pore size selection of 60, 120, 200, 300, 500 and 1000 Å.
The bonding chemistry is from regular C18, C8, C4, Phenyl, Cyano, Amino, Diol, Pyridine, SCX and
SAX to any custom-synthesis. The controlled manufacturing process guarantees high batch-to-batch
reproducibility. Their high surface area and high mechanical strength enable those media ideal for
preparative separation and purification.
Packing
Phases
|
Chemistry
|
Particle
Size
(µm)
|
Pore
Size
(Å)
|
Surface
Area
(m²/g)
|
Carbon
Loading
(%)
|
pH
Stability
|
Bonding
|
C18
|
GP-C18
|
5, 10, 15, 20,
30, 50
|
60
120
|
450
300
|
19
17
|
2-8.5
|
Monomeric and
fully endcapped
|
|
BR-C18
|
5, 10
|
120
|
300
|
19
|
1.5-10.5
|
Fully endcapped
|
|
HP-C18
|
5, 10, 15, 50
|
120
|
300
|
15
|
2-8.5
|
Monomeric and
fully endcapped
|
|
Bio-C18
|
5, 10, 15, 50
|
200
300
|
200
105
|
10
8.5
|
2-8.5
|
Monomeric and
fully endcapped
|
C8
|
GP-C8
|
5, 10, 15, 50
|
60
120
|
450
300
|
15
11
|
2-8.5
|
Monomeric and
fully endcapped
|
|
Bio-C8
|
5, 10, 15, 50
|
300
|
105
|
5.2
|
2-8.5
|
Monomeric and
fully endcapped
|
C4
|
GP-C4
|
5, 10, 15, 50
|
120
|
300
|
8.0
|
2-8.5
|
Monomeric and
fully endcapped
|
|
Bio-C4
|
5, 10, 15, 50
|
300
|
105
|
3.1
|
2-8.5
|
Monomeric and
fully endcapped
|
Phenyl
|
GP-Phenyl
|
5, 10, 15, 50
|
120
|
300
|
11
|
2-8.5
|
Monomeric and
fully endcapped
|
CN
|
HP-Cyano
|
5, 10, 15, 50
|
120
|
300
|
7.0
|
2-8.5
|
Monomeric and
fully endcapped
|
NH2
|
HP-Amino
|
5, 10, 15, 50
|
120
|
300
|
4.2
|
2-8.5
|
Polymeric and
no endcapping
|
SO3H
|
HP-SCX
|
5, 10, 15, 50
|
120
|
300
|
11
|
2-8.5
|
Monomeric and
fully endcapped
|
Silica
|
HP-Silica
|
5, 10, 15, 20,
30, 50, 60
|
60
120
300
|
450
300
100
|
0.0
0.0
0.0
|
2-8.5
|
Activated surface
|
Characteristic
· Available in both reversed and normal phases
· High chemical stability for low leaching
· High loading capacity
· High mechanical strength for multiple packing
· Spherical particles with controlled pore sizes
· Available from grams to multi-Kilogram
· More than 20 different chemistries
Application
Phases
|
Chemistry
|
Applications
|
C18
|
GP-C18
|
Reversed phase separations for pharmaceuticals, nutraceuticals,
natural products, acidic, neutral and basic compounds
|
BR-C18
|
Basic compounds or separations required high pH durability
|
HP-C18
|
Separations at high aqueous mobile phase, pharmaceuticals, vitamins,
natural products, peptides, and polar compounds
|
Bio-C18
|
Separations required large pore size or at high aqueous mobile phase,
pharmaceuticals, vitamins, natural products, peptides, and polar compounds
|
C8
|
GP-C8
|
Reversed phase separations for pharmaceuticals, estrogens,
acidic, neutral and basic compounds
|
Bio-C8
|
Separations required large pore size for pharmaceuticals, vitamins,
proteins, peptides, and polar compounds
|
C4
|
GP-C4
|
Proteins and peptides
|
Bio-C4
|
Separations required large pore size for proteins and peptides
|
Phenyl
|
GP-Phenyl
|
Aromatic compounds, antibiotics, lipids, ring-structured compounds
|
CN
|
HP-Cyano
|
Normal phase separations for pharmaceuticals and polar
organic compounds
|
NH2
|
HP-Amino
|
Sugars, alcohols, vitamins, nucleosides, oligonucleotides,
and anionic compounds
|
SO3H
|
HP-SCX
|
Amine and polyamine containing compounds, nucleotides, and peptides
|
Silica
|
HP-Silica
|
Normal phase or HILIC mode separation for basic compounds,
pharmaceuticals, nutraceuticals, and metabolites
|
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