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MAS-C

● Activate the column with acetonitrile.

● Add the plasma sample into the above tube

● Add eluent and wait for 3-4 min for precipitation

● Apply vacuum to get the solution through the column and collect the solution

.● Add more solution for elution, collect the eluent and combine collected solution, evaporate solvents and reconstitute the sample with mobile phase, for HPLC or LC-MS analysis.

Characteristic of the Method

● In conventional SPE method, interference matrices are adsorbed and then target compounds eluted, but the MAS are only to adsorb impurities

● MAS employ the sorbent modified with different functional groups that could, simultaneously remove a variety of impurities in one step.

● MAS has good separation ability and selectivity for the proteins, peptides, amino acids, phospholipids, and such biological interference matrix.

● By choosing suitable conditions (solvent and pH), most of the biological interference can be removed, and to ensure strong water-soluble substances tested with more than 70% recovery rate, also for further separation of LC-MS detection.

Ordering Info

Production Spec. Application Package Part No.
MAS SPE cartridge 1mL SPE cartridges, used for basic and neutral substances extraction in Plasma and biological samples 100 MSC-B-0301
1mL 100 MSC-B-0601
1mL SPE cartridges, used for acid substances extraction in Plasma and biological samples 100 MSC-A-0301
1mL 100 MSC-A-0601
MAS 96 well plate 30mg/2ml/well 96 well plate, used for basic and neutral substances extraction in plasma and biological samples. 2 MS-B-0302W
30mg/2ml/well 96 well plate, used for basic and neutral substances extraction in plasma and biological samples, design with a filter membrane (can be used in centrifugation) 2 MS-B-0302W
30mg/2ml/well 96 well plate, used for acid substances extraction in plasma and biological samples. 2 MS-A-0302W
30mg/2ml/well 96 well plate, used for acid substances extraction in plasma and biological samples, design with a filter membrane (can be used in centrifugation). 2 MS-A-0302FW
30mg/2ml/well 96 well plate, used for weak acid substances extraction in plasma and biological samples. 2 MS-WA-0302-W
30mg/2ml/well 96 well plate, used for weak acid substances extraction in plasma and biological samples, design with a filter membrane (can be used in centrifugation) 2 MS-WA-0302-FW

Applications

The most convenient and general approach for 
Propranolol in the Serum with MAS-LC-MS 
Result Contrast from Detection on the Amlodipine in the Serum with MAS-SPE and PPT and SPE Respectiv 
MAS-C Protein Precipitate Columns and SLE on the Drug Metabolism Analysis in the Sample of Serum 
Simultaneous Detection of Glipizide and Glibenclamide with MAS

Production	Spec.	Application	Package	Part No.
MAS SPE cartridge	1mL	SPE cartridges, used for basic and neutral substances extraction in Plasma and biological samples	100	MSC-B-0301
	1mL		100	MSC-B-0601
	1mL	SPE cartridges, used for acid substances extraction in Plasma and biological samples	100	MSC-A-0301
	1mL		100	MSC-A-0601
MAS 96 well plate	30mg/2ml/well	96 well plate, used for basic and neutral substances extraction in plasma and biological samples.	2	MS-B-0302W
	30mg/2ml/well	96 well plate, used for basic and neutral substances extraction in plasma and biological samples, design with a filter membrane (can be used in centrifugation)	2	MS-B-0302W
	30mg/2ml/well	96 well plate, used for acid substances extraction in plasma and biological samples.	2	MS-A-0302W
	30mg/2ml/well	96 well plate, used for acid substances extraction in plasma and biological samples, design with a filter membrane (can be used in centrifugation).	2	MS-A-0302FW
	30mg/2ml/well	96 well plate, used for weak acid substances extraction in plasma and biological samples.	2	MS-WA-0302-W
	30mg/2ml/well	96 well plate, used for weak acid substances extraction in plasma and biological samples, design with a filter membrane (can be used in centrifugation)	2	MS-WA-0302-FW