AU200 Bioprocess Analyzer

The AU200 Bioprocess Analyzer is a high-performance online monitoring system designed for the biopharmaceutical and cell culture fields. It enables real-time detection of key metabolites and cell activity parameters in culture media, providing reliable data to support process development, media optimization, and reaction control. Utilizing advanced spectrophotometry, the AU200 delivers precise measurements with simplified maintenance, while its independently configurable detection parameters accommodate a wide range of cell culture and fermentation systems, including mammalian cells, bacteria, yeast, insect cells, and algae.

Equipped with a highly efficient and stable reaction unit, an intelligent sample and reagent management system, and a high-precision micro-sampling unit, the AU200 ensures accuracy and efficiency throughout the testing process. Its fully enclosed photodiode array post-spectroscopy system, combined with dual-wavelength detection, effectively eliminates sample interference and enhances data reliability. In addition, the system’s specialized anti-cross-contamination design and powerful cleaning functions safeguard experimental stability and reproducibility. With a robust liquid handling system and comprehensive data tracking and alarm features, the AU200 not only meets the rigorous requirements of process development but also provides an all-round solution for quality control in biopharmaceutical manufacturing.

2.Features

• 50 semi-permanent UV-transparent hard cuvettes
• Static reaction tray with direct heating and constant temperature design

 

• Reagent tray cooled by semiconductor Peltier, ensuring quality.
• 40 reagent positions, supporting single or double reagents, plug-and-play.
• 40 sample positions, compatible with various EP tubes and sample cups.

 

• Original high-precision integrated ceramic sampler from the USA, digitally controlled stepper motor for optimized performance, quiet and eco-friendly, with accurate dosing.
• Original high-precision sampling needle from Japan, with nano-polished inner and outer walls. Features include liquid level detection, volume tracking, and 3D collision avoidance intelligent functions.

 

• Nano-polished stirring system to ensure thorough reactions
• High-performance cleaning workstation with 6 stages and 18 automatic steps per cycle

 

• Supports automatic sample dilution and automatic calibration dilution
• Real-time monitoring of sample tray, reagent tray, reaction tray, deionized water, and waste status, with comprehensive alarm functions
• Complies with audit trail and data integrity requirements

• World-renowned brand fluidic components: IWAKI liquid pump, SMC solenoid valves, IDEX ceramic integrated syringe, THOMAS peristaltic dosing pump, Tygon fluid tubing, CPC quick connectors.

 

• Fully enclosed photoelectric array post-dispersion system, maintenance-free for life.
• Dual-wavelength detection to eliminate sample interference.
• Original German UV halogen tungsten lamp with a lifespan of up to 2000 hours.

3.Specification