

The SG-DCF series reusable cell dynamic culture flasks, launched by SAGE-BIO, represent a revolutionary upgrade over traditional culture flasks. Specifically designed for 3D dynamic culture scenarios, they are perfectly compatible with the self-developed DARC-G4.0S/P universal gravity environment simulation system. This series offers three specifications: SG-DCF025 (25cm²), SG-DCF075 (75cm²), and SG-DCF150 (150cm²), with the effective growth surface area precisely matching the model designation.
The flask body is constructed from non-toxic, high-temperature-resistant materials and can withstand repeated autoclaving at 125°C. Combined with the detachable ultra-clear glass growth layer, this enables long-term reuse. A core advantage is its ability to establish a low-shear environment, 100% filled with culture medium and free of bubbles. A silicone-based gas exchange membrane exceeding 20mm in diameter ensures highly efficient gas exchange, while an 8mm large feeding port (only 3mm from the growth surface) simplifies sampling operations. The top quick-connect fitting allows for convenient bubble removal.
A high-clarity glass observation window supports real-time microscopic observation, and the fully liquid-filled design ensures the authenticity of optical monitoring. When adapted for use with SAGE's gravity simulation systems, it can be widely applied in dynamic culture research areas such as space medicine and tissue engineering. The gas exchange membrane and one-way valve are single-use consumables and must be replaced according to specifications.
Compared to traditional ordinary culture flasks, this new series of flasks can be sterilized and reused multiple times. The flask body is made of non-toxic, corrosion-resistant material that can withstand repeated high-temperature高压 sterilization at 125°C. It easily enables a 100% fluid-filled, low-shear stress, and bubble-free culture environment, making it suitable for almost all dynamic environment cultures and 3D cultures, representing a innovation over traditional flasks. As a groundbreaking product developed for 3D dynamic culture scenarios, it can be directly compatible with their self-developed DARC-G4.0S/P Universal Gravity Environment Simulation System, effectively addressing the core pain points of traditional flasks in dynamic culture.
Paired with 1mm ultra-thin glass, its optical performance is comprehensively superior to traditional transparent plastic culture flasks, as evidenced by:
1. Optical Advantages of the SG-DCF Dynamic Culture Flask
1.1 The light transmittance of the glass observation window reaches 92%-95%, compared to 88%-92% for traditional Polystyrene (PS) plastic flasks and 90%-95% for Polycarbonate (PC) plastic flasks.
1.2 Optimized Optical Distortion: The glass observation window, manufactured using an air flotation molding process, has an optical distortion index as low as 0.15μrad and a transmitted wavefront distortion PV value of ≤ λ/4 @ 632.8nm (approx. 0.158μm). This reduces optical distortion by 70%-85% compared to traditional plastic flasks (typically 0.5-1μrad), effectively eliminating edge ghosting and speckle interference.
1.3 Enhanced Imaging Fidelity: The combination of the 1mm ultra-thin glass and the fully liquid-filled design increases light intake by 15% compared to plastic flasks, reduces color reproduction error by 60%, and improves cellular detail resolution under the microscope by 20%. The overall authenticity of optical observation is comprehensively enhanced by 30%-40% compared to traditional plastic flasks.
The SAGE-BIO SG-DCF series reusable cell dynamic culture flasks represent a revolutionary upgrade over traditional flasks, specifically designed for 3D dynamic culture scenarios. They are perfectly compatible with SAGE's self-developed DARC-G4.0S/P universal gravity environment simulation systems. Key advantages include the creation of an ideal, 100% fluid-filled, bubble-free, and low-shear stress environment. Its core strengths lie in superior optical performance, highly efficient gas exchange, and exceptional low-adsorption capability.The flask features an ultra-thin glass observation window with high light transmittance and minimal optical distortion. Compared to traditional plastic flasks, it enhances imaging authenticity and cell detail resolution by over 30%, ensuring reliable real-time microscopic observation and high-precision imaging. A large-area silicon-based gas exchange membrane boosts overall gas exchange efficiency by 5-13.9 times with remarkable stability. Furthermore, the Teflon bottle body significantly reduces the adsorption of extracellular vesicles, proteins, and reagents (adsorption rate reduced by over 89%), guaranteeing a pure culture environment and reliable experimental results. Being autoclavable and reusable, coupled with convenient sampling and bubble-removal designs, the SG-DCF series is an ideal tool for cutting-edge dynamic culture research in space medicine, tissue engineering, and drug screening.
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