Collagen I protein is the most abundant collagen in the human body, making up around 90% of the total collagen in vertebrates. It is a major structural component of connective tissues, including skin, tendons, ligaments, bones, and the organic part of teeth. Collagen I is composed of a triple helix structure formed by two 伪1 chains and one 伪2 chain encoded by the COL1A1 and COL1A2 genes, respectively. This protein provides significant tensile strength and elasticity to tissues, allowing them to withstand mechanical stress. Its synthesis involves complex processes, including transcription, translation, post-translational modifications, and assembly into collagen fibers. Due to its high biocompatibility and unique physical properties, Collagen I is widely used in pharmaceuticals, regenerative medicine, and clinical applications.
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