CD8伪 is a crucial immune glycoprotein that serves as a co-receptor for the MHC I-peptide complex, facilitating the recognition of antigens presented by APCs (antigen-presenting cells) to T cells. It is a key component of the CD8 receptor complex, which is predominantly found on cytotoxic T lymphocytes (CTLs). CD8伪 can form either an 伪/尾 heterodimer with CD8尾 or an 伪/伪 homodimer, both of which play essential roles in CTL activation and function. By interacting with the TCR (T cell receptor) and MHC I molecules, CD8伪 helps recruit the LCK kinase, initiating multiple signaling pathways that drive the CTL-mediated immune response.
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