Phospho-Histone H2A.X (Ser139) Recombinant Rabbit mAb (S-1368-15),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	Phospho-Histone H2A.X (Ser139)
Immunogen	Synthetic Peptide
Location	Nucleus
Accession	P16104
Clone Number	S-1368-15
Antibody Type	Recombinant mAb
Isotype	IgG
Application	WB, IHC-P, IP
Reactivity	Hu, Ms, Rt
Purification	Protein A
Concentration	0.5 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
Dot Blot	1:1000
WB	1:1000
IP	1:50
IHC-P	1:200-1:500

Background

Phospho-Histone H2A.X (Ser139), also known as γH2A.X, is a variant of the histone H2A protein that plays a crucial role in the cellular response to DNA double-strand breaks (DSBs). When DNA damage occurs, such as that induced by ionizing radiation or anticancer drugs, the protein is rapidly phosphorylated at Ser139 by kinases like ATM, ATR, and DNA-PK. This phosphorylation event is one of the earliest responses to DNA damage and is essential for the recruitment of various DNA repair proteins to the site of the break.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.