CD24 is a small cell surface glycoprotein that belongs to the mucin-like family of proteins. It is expressed on various cell types, including hematopoietic stem cells, epithelial cells, endothelial cells, and a subpopulation of lymphocytes and monocytes. CD24 is involved in cell-cell interactions and cell adhesion. It can interact with other cell surface molecules, such as P-selectin, and play a role in cell migration and adhesion. CD24 expression is also associated with cancer progression and metastasis. It is overexpressed in many tumor types, including breast cancer, ovarian cancer, and colorectal cancer, and is often associated with poor prognosis. CD24 has been shown to regulate cell proliferation, apoptosis, and differentiation. It can activate signaling pathways, such as the PI3K/Akt pathway, and influence cellular responses to growth factors and cytokines.
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