Histone H3 crotonylation, specifically at lysine 9 (H3K9cr), is a form of post-translational modification that has been identified as a key player in epigenetic regulation, particularly in plants 。This modification is structurally and functionally distinct from the well-studied lysine acetylation and is involved in various biological processes, including chromatin remodeling, metabolism, cell cycle, and cellular organization. In the context of histones, crotonylation can be found on different lysine residues among plant species and is known to overlap with the histone modification H3K9ac in about 95% of the regions, which suggests a potential interplay between these two modifications.
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