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Brefeldin A
Brefeldin A
Place of Origin:
China
Brand:
CHEMLEADER
Model:
20350-15-6
Supplier:
Chemleader Biomedical Co.,Limited
Price:
Hits:
229 
Updated:
4/30/2025
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    Brefeldin A（BFA）CAS No.20350-15-6                                                                                       Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus.Brefeldin A is also an autophagy and mitophagy inhibitor.Brefeldin A is a CRISPR/Cas9 activator.Brefeldin A inhibits HSV-1 and has anti-cancer activity.
    Products are for research use only. Not for human use. We do not sell to patients. 

    [1] R D Klausner ，et al. Brefeldin A: insights into the control of membrane traffic and organelle structure. J Cell Biol. 1992 Mar;116(5):1071-80. (doi: 10.1083/jcb.116.5.1071.)

    [2] Julie G. Donaldson, et al. Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein. Nature volume 360, pages350–352 (1992).

    [3] Antonino Colanzi，et al.Molecular mechanism and functional role of brefeldin A-mediated ADP-ribosylation of CtBP1/BARS. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9794-9. (doi: 10.1073/pnas.1222413110. Epub 2013 May 28.)

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    ChemLeader Biomedical Co.,Limited was founded in 2010, is a professional research chemical supplier specializing in R&D, manufacturing and sales. The headquarters is located in Shanghai International Medical Zone(SIMZ), Pudong New District, Shanghai, China, with over 30000 square feet sales office/ research laboratory and 20000 square feet pilot plant. Our branches in Xuzhou, Shandong, and Hong Kong.

    We are committed to provide the highest quality products and the best service to pharmaceutical company and scientific research institutions in China and international markets. Our team has had extensive expertise and an excellent background in synthetic chemistry, project management, CRO, QC/QA, pilot plant etc.

    As an innovation-driven and customer-focused company, we also specialize in custom synthesis of organic compounds, various drug intermediates as well as a variety of specialty and fine chemicals ranging from milligram to tons scale.

    With our whole Professional team's efforts for many years we gain the admiration and trust from the domestic and overseas clients, and favorable position and Reputation in China Pharmaceutical and Fine Chemicals field. We are devoted to decreasing the production cost, optimizing the artwork, creating and keeping the accomplishment of best environmental, health, and safety performance in the industry.
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