Laser speckle blood flow imager,Laser speckle blood flow imager_specification/price/image

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Experimental Animal Laser Speckle Blood Flow Imager
The system is built around the emerging Laser Speckle Contrast Imaging (LSCI) technique. By virtue of its unique, non-contact, high-resolution, full-field and ultra-fast imaging capabilities, it provides clinicians and life-science researchers with a completely new and effective tool for real-time blood-flow monitoring and perfusion mapping.

Principle
LSCI extracts the velocity of moving particles (e.g., red blood cells) from the dynamic speckle pattern created when coherent laser light scatters from optically rough tissue. A CCD or CMOS camera continuously records the illuminated area, and spatial–temporal contrast analysis of the raw speckle images yields a two-dimensional map of relative blood flow without the need for any contrast agent.

Shanghai Yuyan LS-series Laser Speckle Perfusion Imagers deliver millisecond-level temporal resolution and micrometre-level spatial resolution, enabling researchers and clinicians to observe microvascular flow distribution and relative flow changes in real time. The large field-of-view optics cover everything from small animals (mice, rats) through large animals (pig, canine) to human subjects.

System Components

Laser speckle main unitHigh-performance image & data processor

Model: LS-200

Key Features

Ultra-high imaging fidelity: resolves cerebral end-capillaries in mice under standard settings.
Industry-leading response: <200 ms latency, the fastest among comparable systems; instantaneous display of occlusion/reperfusion events.
Compact data footprint: ≈3 MB per file; hours of continuous recording possible thanks to 20-year algorithm optimisation.
One-piece microscope integration: real-time perfusion image appears while you operate under the microscope—no additional optics required.
Stable working distance: once focused, the field of view remains spatially locked, simplifying surgical manipulation.
Glare-free illumination: proprietary side-fired laser delivery eliminates specular reflection; no saline overlay needed.
User-friendly software: <30 min learning curve; fully optimised internal parameters; free-hand ROI selection, copy, drag, edit; automatic report generation (histograms, line graphs, tables).

Technical Highlights
Laser speckle: When coherent laser light strikes a tissue surface that is rough on the scale of the wavelength, multiply-scattered waves interfere to produce a random granular pattern—the speckle. If the scattering medium (blood cells) moves, the speckle intensity at each pixel fluctuates in time. Spatial–temporal statistics of these fluctuations are converted into quantitative flow maps.

Core Specifications

Parameter	LS-200	LS-150
Laser wavelength	785 nm	785 nm
Working distance	100 – 500 mm	100 – 250 mm
Camera resolution	2048 × 2048	2048 × 2048
Flow-imaging speed	>100 fps	>100 fps
Focus	Auto	Manual
Imaging modes	High-resolution & Fast	High-resolution & Fast
Image registration	Tissue outline / Colour photo / Flow overlay
ROI mean-flow analysis	Select, copy, delete, drag, edit
TOI analysis	Mean flow & relative change
Pixel density	8.4 million pixels/cm²
Event marking	Real-time flag insertion
Data formats	Raw flow, standard images, video