Human antithrombin, prepared from human plasma, inactivates factor IIa (thrombin) and factor Xa, therefore can be used to determine the anti-FIIa and anti-FXa activities of heparin and LMWHs.
Applications
Human antithrombin can be used in many applications, such as:
1. Anti-factor Xa activity to anti-factor IIa activity ratios of heparin and LMWHs
2. Anti-factor IIa activities and anti-factor Xa activities of heparin and LMWHs
3. As a research reagent to investigate coagulation-related species
Composition
Human antithrombin is in form of white lyophilized powder stored in vials. Each vial contains: Human antithrombin 10 IU; Tris 60.5 mg.
Physical and Chemical Properties
Appearance: white lyophilized powder
Purity: electrophoretic purity
Molecular weight: about 56 kDa
E1cm1%(280 nm): about 10
Specific activity: not less than 6 IU/mg
Standard: 10 IU
Usage
Reconstitute the entire contents of a vial, dissolve it with 10 mL distilled water to get a solution with concentration of 1 IU/mL human antithrombin, pH 7.4.
Stability and Storage: The lyophilized powder of human antithrombin could be preserved at 2 to 8 °C for 12 months. The 0.25 IU/mL human antithrombin solution could be preserved at 2 to 8 °C for about 1 month.
bio-equip.cn
中文
