| Cell Line Description |
The Vero cell line was established in 1962 from cells extracted from the kidneys of African green monkeys. Since then, several sub-cell lines have been derived, such as Vero 81, Vero 76 or Vero E6. Later genomic analysis showed that these cells originated from females of the species Chlorocebus sabaeus. The Vero cell line is a continuous cell line and can therefore be passaged indefinitely, allowing for extensive cell characterization and the creation of large cell banks, a valuable advantage over primary cell lines with limited passage capacity, such as chicken embryo fibroblasts. Vero cells grow adherently, are deficient in interferon expression and can be adapted to grow in serum-free conditions. Vero is susceptible to infection with a wide range of viruses, such as SV-40, measles virus, arboviruses, rubella virus, poliovirus, influenza virus and simian syncytial virus. It is also susceptible to bacterial toxins, including diphtheria toxin and Shiga-like toxin. They are widely used in many research fields, especially virology, bacteriology, parasitology and toxicology. |
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