ZH-6C Intelligent cold plate pain threshold detector is an instrument developed for screening acute pain and analgesic drugs, flick reflex test or plantar tenderness test. But these are the normal threshold of stimulus response in animals and belong to a kind of physiological pain. There are essential differences between physiological pain and pathological pain. Physiological pain is a set of alarm systems for self protection for survival, and pathological pain is a disease that prevents survival. Because of the difference between the two kinds of pain and the mechanism, the experimental methods of analgesic drugs are different. For example, some analgesic drugs have good analgesic effects on physiological and pathological pain. But some drugs only have effects on physiological pain, so different experimental methods and instrument can be used to screen different drugs with different action points. ZH-6C Intelligent cold plate pain threshold detector is an instrument that can perform physiological pain experiments and pathological pain experiments on the same instrument.
When the panel temperature of the ZH-6C type cold and hot plate analgesia meter is set to 4 ℃, the drug can obviously change the foot lifting time and frequency of the animals with pathological pain model on the cold plate. When the panel temperature is set to 55 ℃, high and low of the animals' physiological pain threshold can be accurately measured, so as to determine the type and effect of the test drug's analgesia.
The advantage of experimental method is that the animals are tested in an unrestricted state, avoiding artificial interference and harm to the animals. Because of its simple operation, clear indicators and more accurate reflection of animals' pain behavior, it is favored by the experimenters. In addition to the basic requirements of wide temperature setting (-10 ℃ ~ 80 ℃) high temperature control accuracy (±0.2 ℃), small timing error (precision 0.01 second), this instrument also has the advantages of LCD screen display built-in micro printer, USB interface and quick loading of animals, complete data display, convenient observation of animals, automatic calculation of foot lifting time and foot lifting frequency, etc. is a real one-machine-for-two analgesic drug experimental instrument.
Technical parameters
01. Adaptable animals: rats, mice, guinea pigs
02. Animal observation transparent cage: diameter 24mm x 245mm
03. Hot/cold plate size: diameter 230mm
04. Display mode: 7-inch high-definition screen display
05. Temperature setting range: -10℃~ 80℃, adjustment step 0.1℃
06. Temperature control error: ±0.2℃
07. Time control mode: touch key, foot pedal switch
08. Time display: minute: second: millisecond
09.ing accuracy: 0.01 second
10. Heating time: about 2 minutes (from 20℃ to 55℃)
11 Cooling time: about 3 minutes (from 20℃ to 4℃)
12. Dual recording mode: timing mode, counting mode
13. Rec information: experiment time, experiment temperature, animal properties, experiment group, timing time, counting times, experiment mode, experiment group type
14. Storage environment temperature: ±0℃~ 50℃
15. Use environment temperature: 15℃ ~30℃, recommended temperature around 20℃
16. Use environment: 20% RH ~ 75% RH
17. Printing method: built-in printer storage and print
18. Maximum memory data: 0 groups, 20 records per group
19. Data output: data export via USB flash drive
20. Power requirements: AC 220V,50Hz
21. Input power: 300W
23. Volume: 385mm (length) x 295mm () x 210mm (height)
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