Rat Vascular Endothelial cell Growth Factor C (VEGF-C) ELISA Kit,Abbkine_specification/price/image

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Vascular endothelial growth factor receptor-1 was originally discovered through the screening of a human placental cDNA library . It is a receptor tyrosine kinase (RTK) specific for the angiogenic factors VEGF (VEGF-A), PlGF, and VEGF-B. VEGF R1 is expressed in two forms via alternate splicing at the pre-mRNA level: a full-length, membrane bound receptor capable of transducing signal, and a truncated, soluble receptor (sVEGF R1) capable of sequestering ligand or dimerizing with full-length receptor and preventing signal transduction.Although VEGF R1 null mutations are lethal, deletions of the kinase domain are not, suggesting that the soluble form, or at least the extracellular domain, is all that is necessary for normal vascular development.

Rat Vascular Endothelial cell Growth Factor C (VEGF-C) ELISA Kit employs a two-site sandwich ELISA to quantitate VEGFC in samples. An antibody specific for VEGFC has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyVEGFC present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for VEGFC is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of VEGFC bound in the initial step. The color development is stopped and the intensity of the color is measured.

Rat Vascular Endothelial cell Growth Factor C (VEGF-C) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/rat-vascular-endothelial-cell-growth-factor-c-vegf-c-elisa-kit-kte100010/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.