Mouse Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (SDHA) ELISA Kit,Abbkine_specification/price/image

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SDHA encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29.Hirawake et al. (1994) isolated a cDNA corresponding to the flavoprotein subunit of SDH from a human liver cDNA library. The deduced 621-amino acid protein has a molecular mass of approximately 68 kD and shows high homology to the bovine heart flavoprotein subunit.

Mouse Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (SDHA) ELISA Kit employs a two-site sandwich ELISA to quantitate SDHA in samples. An antibody specific for SDHA has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySDHA present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SDHA is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SDHA bound in the initial step. The color development is stopped and the intensity of the color is measured.

Mouse Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (SDHA) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/mouse-succinate-dehydrogenase-ubiquinone-flavoprotein-subunit-mitochondrial-sdha-elisa-kit-kte70470/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.