Mouse SDHD ELISA Kit,Abbkine_specification/price/image

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SDHD, which stands for succinate dehydrogenase complex subunit D, is one of the two transmembrane subunits of the four-subunit succinate dehydrogenase protein complex that resides in the inner mitochondrial membrane. It also refers to the gene that codes for this protein.Germline mutations in SDHD were first linked to hereditary paraganglioma in 2000. Since then, it has been shown that mutations in SDHB and to a lesser degree SDHC can cause paranglioma as well familial pheochromocytoma. Notably, the tumor spectrum is different for the different mutations. SDHB mutations often lead to metastatic disease that is extra-adrenal, while SDHD mutation related tumors are more typically benign, originating in the head and neck.

Mouse Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (SDHD) ELISA Kit employs a two-site sandwich ELISA to quantitate SDHD in samples. An antibody specific for SDHD has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySDHD present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SDHD is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SDHD bound in the initial step. The color development is stopped and the intensity of the color is measured.

Mouse Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (SDHD) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/mouse-succinate-dehydrogenase-ubiquinone-cytochrome-b-small-subunit-mitochondrial-sdhd-elisa-kit-kte70467/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.