Human Receptor II for the Fc region of immunoglobulin G (FcGRII) ELISA Kit,Abbkine_specification/price/image

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CD32 is a surface receptor protein and part of a large population of B cell co-receptors. It has a low-affinity for IgG antibodies and down-regulates antibody production in the presence of IgG. This feedback loops essentially lowers the production of IgG produced by B cells when there is a surplus in the body.Monoclonal antibodies can distinguish between type A and type B.Receptors for the Fc portion of IgG such as FCGR2A play an essential role in the protection of the organism against foreign antigens by removing antigen-antibody complexes from the circulation. Receptors are present on monocytes, macrophages, neutrophils, natural killer (NK) cells, and T and B lymphocytes, and they participate in diverse functions such as phagocytosis of immune complexes and modulation of antibody production by B cells.

Human Receptor II for the Fc region of immunoglobulin G (FcGRII) ELISA Kit employs a two-site sandwich ELISA to quantitate FcGRII in samples. An antibody specific for FcGRII has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyFcGRII present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FcGRII is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FcGRII bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Receptor II for the Fc region of immunoglobulin G (FcGRII) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-receptor-ii-for-the-fc-region-of-immunoglobulin-g-fcgrii-elisa-kit-kte62638/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.