Annexin 2 is involved in diverse cellular processes such as cell motility (especially that of the epithelial cells), linkage of membrane-associated protein complexes to the actin cytoskeleton, endocytosis, fibrinolysis, ion channel formation, and cell matrix interactions. It is a calcium-dependent phospholipid-binding protein whose function is to help organize exocytosis of intracellular proteins to the extracellular domain. Annexin II is a pleiotropic protein meaning that its function is dependent on place and time in the body. This protein is a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption.
Human Annexin A2 antibody (ANXA2-Ab) ELISA Kit has been pre-coated with an antibody specific to ANXA2-Ab. Standards or samples are then added to the appropriate microtiter plate wells with a Horseradish Peroxidase (HRP)-conjugated ANXA2-Ab and incubated. The competitive inhibition reaction is launched between with HRP labeled ANXA2-Ab and unlabeled ANXA2-Ab with the antibody. A substrate solution is added to the wells and the color develops in opposite to the amount of ANXA2-Ab in the sample. The color development is stopped and the intensity of the color is measured.
Human Annexin A2 antibody (ANXA2-Ab) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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