CYFIP1 encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization.This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including CYFIP1 is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion.
Human Cytoplasmic FMR1-interacting protein 1 (CYFIP1) ELISA Kit employs a two-site sandwich ELISA to quantitate CYFIP1 in samples. An antibody specific for CYFIP1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyCYFIP1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CYFIP1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CYFIP1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Human Cytoplasmic FMR1-interacting protein 1 (CYFIP1) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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