Human Potassium voltage-gated channel subfamily A member 2 (KCNA2) ELISA Kit,Abbkine_specification/price/image

Product Detail
Company Profile

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). KCNA2 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of KCNA2 is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.

Human Potassium voltage-gated channel subfamily A member 2 (KCNA2) ELISA Kit employs a two-site sandwich ELISA to quantitate KCNA2 in samples. An antibody specific for KCNA2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyKCNA2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for KCNA2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of KCNA2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Potassium voltage-gated channel subfamily A member 2 (KCNA2) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-potassium-voltage-gated-channel-subfamily-a-member-2-kcna2-elisa-kit-kte61929/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.