MUC20 encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The C-terminus of this family member associates with the multifunctional docking site of the MET proto-oncogene and suppresses activation of some downstream MET signaling cascades. The protein features a mucin tandem repeat domain that varies between two and six copies in most individuals. Multiple variants encoding different isoforms have been found for MUC20. A related pseudogene, which is also located on chromosome 3, has been identified.
Human Mucin-20 (MUC20) ELISA Kit employs a two-site sandwich ELISA to quantitate MUC20 in samples. An antibody specific for MUC20 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyMUC20 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MUC20 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MUC20 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Human Mucin-20 (MUC20) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/human-mucin-20-muc20-elisa-kit-kte61457/
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