PABPC1L belongs to the polyadenylate-binding protein type-1 family. Recent linkage studies and association analyses indicate the presence of at least one type 2 diabetes susceptibility gene in human chromosome region 20q12-q13.1. The map currently provides near-continuous coverage between SGC32867 and WI-17676 .EST database searches and genomic sequence alignments of ESTs, mRNAs, and UniGene clusters enabled the annotation of the sequence interval with experimentally confirmed and putative transcripts. The combination of the BAC transcript map, YAC-to-BAC scaffold, and reference Human Genome Project sequence provides a powerful integrated resource for future genomic analysis of this region.
Human Polyadenylate-binding protein 1-like (PABPC1L) ELISA Kit employs a two-site sandwich ELISA to quantitate PABPC1L in samples. An antibody specific for PABPC1L has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPABPC1L present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PABPC1L is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PABPC1L bound in the initial step. The color development is stopped and the intensity of the color is measured.
Human Polyadenylate-binding protein 1-like (PABPC1L) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/human-polyadenylate-binding-protein-1-like-pabpc1l-elisa-kit-kte61322/
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