AMSBIO: Induced Pluripotent Stem Cells for Regenerative Research

AMSBIO announces that induced pluripotent stem (iPS) cell expert - Dr Masato Nakagawa from the Nobel Prize winning Yamanaka Lab** at the Centre for iPS Cell Research and Application, Kyoto University, Japan will give 3 talks in the UK on the 10th and 11th December 2018.

Appearing at the Wellcome Genome Campus (Cambridge), the MRC Centre for Regenerative Medicine (Edinburgh) and at Guys Hospital (London) - Dr Nakagawa will present a talk on how to obtain well-reprogrammed and uniform human iPSCs using a combination of efficient reprogramming systems with a xeno-free and feeder-free culture system (StemFit®) 

Human embryonic stem cells (hESCs) and iPSCs hold promise as powerful tools for regenerative medicine, however traditional culture methods using feeder cells and other animal derived products present numerous safety concerns when applying reprogrammed cells to clinical applications. To address these issues, Dr Nakagawa presents a novel culture system for hESCs and iPSCs using a combination of StemFit® and additional animal free cell culture materials. In his presentation he describes how this efficient method of producing cells for both research and clinical applications, offers a simple, reproducible method for the reprogramming of somatic cells and rapid expansion of single cell clones to produce clinical-grade iPSCs.
 
In a recent independent study++, media of different formulations were compared with StemFit® for culturing iPS cells. The resultant research data showed, iPS cells cultured with StemFit® offered higher cell proliferation, lower lactate accumulation and demonstrated better homogeneity of gene expression compared with iPS cells cultured with 4 other media.

AMSBIO is the leading international supplier of StemFit® products. For further information please visit http://www.amsbio.com/Feeder-Free-Stem-Cell-Culture.aspx or contact AMSBIO on +44-1235-828200/ +1-617-945-5033 /info@amsbio.com.

Founded in 1987, AMS Biotechnology (AMSBIO) is recognized today as a leading company contributing to the acceleration of discovery through the provision of cutting-edge life science technology, products and services for research and development in the medical, nutrition, cosmetics and energy industries. AMSBIO can draw upon in-depth expertise in extracellular matrices to provide elegant solutions for studying cell motility, migration, invasion and proliferation. Widely acknowledged as an expert in cell culture, AMSBIO partners with clients in tailoring cell systems to enhance organoid and spheroid type screening outcomes from a technological and cost-effective perspective.

** Yamanaka's Nobel Prize–winning research in iPS cells. The 2012 Nobel Prize in Physiology or Medicine was awarded jointly to Sir John B. Gurdon and Shinya Yamanaka "for the discovery that mature cells can be reprogrammed to become pluripotent."

https://www.nature.com/articles/srep03594

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