Millipore Introduces New Antibody Purification Tools

Millipore Corporation today introduced two purification tools that enable life science researchers to perform small scale purifications faster and easier than before.
New PureProteome™ Protein A and Protein G Magnetic Beads provide the highest binding capacity commercially available, allowing for the greatest recovery of protein.

In addition, the PureProteome Magnetic Beads ensure reproducible separation of immunoglogulins (IgG) by allowing for total removal of buffers and complete recovery of beads.

"With PureProteome bead’s higher binding capacities and faster kinetics, researchers can now purify up to 6 times more IgG from serum in half the time,” said Maria Wasienko, Product Manager for Protein Detection at Millipore.

Coated beads are an established method for isolating IgG in immunoprecipitation or serum depletion assays. Purifications are often performed using agarose beads, which require centrifugation to pellet the sample to the bottom of the tube followed by aspiration steps which leads to sample loss and variable results.

Magnetic beads were developed to ensure rapid and reproducible purifications by immobilizing the beads to the side of the tube allowing for total removal of buffers with no loss of sample. However, magnetic beads have had significantly lower binding capacities than other bead-based purification media. PureProteome beads overcome this limitation by binding higher amounts of IgG.

PureProteome beads are available with an optional magnetic rack that immobilizes the beads against the side of the tube in seconds, allowing for reproducible purifications to be performed quickly and easily.

About Millipore

Millipore (NYSE: MIL) is a Life Science leader providing cutting-edge technologies, tools, and services for bioscience research and biopharmaceutical manufacturing. As a strategic partner, we collaborate with customers to confront the world’s challenging human health issues. From research to development to production, our scientific expertise and innovative solutions help customers tackle their most complex problems and achieve their goals. Millipore Corporation is an S&P 500 company with more than 6,000 employees in 47 countries worldwide. For more information, visit www.millipore.com