Precision Multichannel Pipetting Enables Fast & Economic 3D Microtissue Cultivation

INTEGRA, in association with Insphero (Zurich, Switzerland), have released an application note** that describes how a precise pipetting technology enables the efficient use of a hanging drop culture system overcoming many of the drawbacks of conventional cell culture techniques.

 

Cells cultured in standard suspension or monolayer culture typically lose many features that are characteristic of cells in tissue and limit their use to study certain aspects of cell biology. The major differences to in vivo growth conditions of cells include the absence or limited interaction of cell-cell interaction and cell-matrix interaction, a lack of three-dimensional architectural appearance and changed hormonal, nutritional and physical environment.

 

The application note describes how Insphero's unique hanging drop cell culture system is used to generate a diverse range of microtissues. This microtissue system is based on the innovative GravityPlus culture platform for which multichannel pipettes have to be used for the efficient liquid media exchange of the culture drops. Through extensive working and testing of the drop culture system the researchers demonstrate how the versatility and precision of INTEGRA VIAFLO electronic pipettes allows fast and economic cultivation of the cells in hanging droplets.

For Insphero the outstanding tip fitting providing precise positioning of the tips was one of the key reasons for using the INTEGRA Viaflo pipettes as it guaranteed precise connection of all tips to the bores on their GravityPlus platform.

 

This application is an example of the unmatched multichannel dispensing precision achievable using INTEGRA Viaflo pipettes with the GripTip system.

For a copy of this application note please contact INTEGRA Biosciences AG on telephone +41-81-286-9530 or by email info@integra-biosciences.com. In the USA please contact Viaflo Corporation on telephone +1-603-578-5800 or by email loneil@viaflo.com.

 

Worldwide HQ

INTEGRA Biosciences AG
Zizers, Switzerland

Tel: + 41 81 286 9530
Email: info@integra-biosciences.com
www.integra-biosciences.com

 

USA

 

INTEGRA Biosciences Corporation

Hudson, NH 03051

USA

tel. +1 603 578 5800

Email: loneil@viaflo.com

www.viaflo.com