Pall introduces new technologies at the Biotech & Pharm China show this week

New Hybrid Filters Accelerate Processing of High-Yield Biotech Drugs

East Hills, NY (April 26, 2006) - - Biotechnology companies are making significant advances in production of higher concentrations of proteins critical to meeting the demand for life-saving therapies. Despite this advance, production bottlenecks remain because standard filtration technologies lack the ability to perform economically at high flow rates in these high concentration solutions. Working to meet the challenge faced by one of the world’s leading biotechnology companies, Pall Corporation (NYSE: PLL) developed two new filtration technologies that significantly improve production throughput for protein-based biotech drugs. The new Supor® UEKV and new Fluorodyne® EX high flow sterilizing grade cartridge filters are each unique hybrids that offer the biotech industry cost-effective solutions to processing challenges.

View the complete press release at our website.

 

New Process Optimization Technologies from Pall Enable Faster and More

Accurate Process Development with Smaller Volumes and Data Logging

East Hills, NY (April 26, 2006) - - Testing protein solutions to determine processing conditions for full-scale manufacturing has become very expensive for drug discovery and research laboratories, due to the low available volumes of these solutions in the early stages of the drug life-cycle. To address the critical need for affordable testing equipment that can reliably process small sample volumes, Pall Corporation (NYSE: PLL) has launched two new Tangential Flow Filtration (TFF) systems. The new Minim™ II and new Centramate™ 500 TFF systems enable laboratories to test ultra-low-solution volumes when determining true scale-up conditions. This optimizes processes and reduces development times.  Additionally, the systems provide data-logging to meet increasingly strict regulatory requirements for process design (DQ) validation.

 

View the complete press release at our website. 
 

New Hydraulic Chromatography Column Automates

Maintenance and Improves Drug Processing Safety

East Hills, NY (April 26, 2006) - - Column chromatography is a critical purification step in downstream processing of biopharmaceuticals. However traditional systems require significant downtime and labor to disassemble components for routine maintenance, resulting in production bottlenecks. Pall Corporation (NYSE:PLL) helps processors overcome this challenge with the new Resolute™ DAP column chromatography system, which features an innovative hydraulic lifting mechanism for automatic column disassembly. This system significantly streamlines cleaning and improves operational safety, cutting routine maintenance time by as much as two-thirds. The Resolute DAP system offers manufacturers a flexible solution for multi-use operations such as those found in contract drug manufacturing, where quick and safe maintenance between drug batch processing is essential.

View the complete press release at our website.

 

Bench-top Chromatography System Speeds Process Development of New Drugs

 

East Hills, NY (April 26, 2006) - - Cell separation and protein purification sequences in the laboratory are critical components of process development for new therapies requiring multiple steps that are often labor-intensive and time-consuming.  Pall Corporation (NYSE: PLL) is introducing a new bench-top system that automates the process, significantly improving laboratory efficiency and cutting down drug development time by weeks or even months.  The new PKL Chromatography System automates laboratory chromatography, the scientific methodology of separating biologics, enabling operations on a 24-hour continuous basis.  This flexible laboratory tool performs process optimization for new drugs used in clinical trials and small-scale production.  In addition to improving productivity, it also provides a roadmap for easy drug production scale-up.

View the complete press release at our website.