Gentle and Rapid Detachment of Even Delicate Adherent Cells

Hits:51   Date: 11/18/2025

Detachin™ Cell Detachment Solution from Amsbio provides a superior alternative to Trypsin/EDTA for gentle detachment of adherent cells from in vitro growth vessels.

 
Widely cited in recent published papers1, 2, 3, 4 - Detachin™ is proven to quickly deliver gentle detachment of a wide variety of adherent cells, including primary cell types and delicate culture systems, from any tissue culture plasticware. These papers involving primary immune cells, patient-derived cancer models, engineered mammalian lines and high-throughput screening systems, provide further evidence for gentle cell detachment using Detachin - which is shown to maintain phenotypic accuracy and downstream assay reproducibility. In addition, this growing body of evidence demonstrates how Detachin™ enhances cell integrity in diverse and demanding next-generation adherent cell workflows.

 
The proprietary Detachin™ formulation contains protease and collagenase activities in an isotonic phosphate buffer solution with EDTA. It has been tested successfully on many different primary cells and cell lines, including: bone marrow cells, stem cells, fibroblasts, hepatocytes, mouse germ cells, keratinocytes, macrophages, chick embryo cells, neuronal cells, vascular endothelial cells, A-375, BHK, CHO, COS, D54, HEK293, HeLa, L-929, M-24, MG-63, MRC-5, NIH-3T3, NT-2 cells, U-251, Vero, Sf9 insect cells, and many others.
 
Stable at 4°C for 2 months, not only does Detachin™ Cell Detachment Solution offer unmatched cell viability, but it also produces no mammalian or bacterial byproducts meaning there is no need to wash your detached cells. Offered in a range of convenient formats and sizes - Detachin™ provides an economic solution to labs regularly tasked with cell detachment protocols.
 
For further information on Detachin™ Cell Detachment Solution please visit https://www.amsbio.com/detachin-cell-detachment-solution/ or contact Amsbio on +31-72-8080244 / +44-1235-828200 / +1-617-945-5033 / info@amsbio.com.
 
Now part of the Europa Biosite group of companies, AMS Biotechnology (Amsbio) is recognized as a leading transatlantic company contributing to the acceleration of discovery through the provision of cutting-edge life science technology, products, and services for R&D in the medical, nutrition, cosmetics, and energy industries. Amsbio has in-depth expertise in extracellular matrices to provide elegant solutions for studying cell motility, migration, invasion, and proliferation. This expertise in cell culture and the ECM allows Amsbio to partner with clients in tailoring cell systems to enhance organoid and spheroid screening outcomes using a variety of 3D culture systems, including organ-on-a-chip microfluidics. For drug discovery research, Amsbio offers assays, recombinant proteins, and cell lines. Drawing upon a huge and comprehensive biorepository, Amsbio is widely recognized as a leading provider of high-quality tissue specimens (including custom procurement) from both human and animal tissues. The company provides unique clinical grade products for stem cells and cell therapy applications. This includes GMP cryopreservation technology, and high-quality solutions for viral delivery.
 
References:
1. Cells (MDPI, 2023, 13(1):82): https://www.mdpi.com/2073-4409/13/1/82
2. Nature Scientific Reports (2024, s41598-024-76482-y): https://www.nature.com/articles/s41598-024-76482-y
3. Cells (MDPI, 2024, 12(23):2707): https://www.mdpi.com/2073-4409/12/23/2707
4. bioRxiv preprint (Mar 2025, 10.1101/2025.03.20.642115v2): https://www.biorxiv.org/content/10.1101/2025.03.20.642115v2.abstract
---------------------

Worldwide HQ

AMS Biotechnology (Amsbio)
184 Milton Park
Abingdon
Oxon OX14 4SE
UK
Tel: +44-1235-828200
Fax: +44-1235-820482
Email: info@amsbio.com
Web www.amsbio.com
 
North American HQ
 
Amsbio LLC
1035 Cambridge Street
Cambridge
MA 02141
USA
Tel: +1.617.945.5033
Tel: +1.800.987.0985 (toll free)
Email: info@amsbio.com 
Web: www.amsbio.com