True influenza is an acute infectious disease caused by a member of the orthomyxovirus family: influenza virus A, B or, to a much lesser extent, influenza virus
C. Influenza outbreaks usually occur in the winter in temperate climates. Major
outbreaks of influenza are associated with influenza virus type A or B. Infection with
type B influenza is usually milder than type A. Type C virus is associated with minor
symptoms.
The virus is spread person to person via small particle aerosols (less than 10μm
diameter) that can get into respiratory tract. It can also survive for a short time on
surfaces and can be spread by this route if the virus is introduced into the nasal
mucosa before it loses infectivity. Virus concentration in nasal and tracheal secretions
remains high for 24 to 48 hours after symptoms start and may last longer in children.
Titers are usually high and so there are enough infectious virions in a small droplet to
start a new infection.
The internal antigens (M1 and NP proteins) are the type-specific proteins
(type-specific antigens) used to determine if a particular virus is A, B or C. The M1
proteins of all members of each type show cross reactivity. The NP proteins of all
members of each type also show cross reactivity.The external antigens (HA and NA)
show more variation and are the subtype and strain-specific antigens.
We have screened out anti-influenza A virus monoclonal antibodies and anti-influenza
B virus monoclonal antibodies of high activity, which can be used in rapid test and
ELISA assays.
Product name Description Application
Anti-Flu A Liquor One pair, including coating antibody and label
antibody; used in ELISA or rapid test
Anti-Flu B Liquor One pair, including coating antibody and label
antibody; used in ELISA or rapid test
bio-equip.cn
Beijing Hotgen Biotech Co.,Ltd, which is located in Beijing Zhongguancun High-tech
development zone, is a high-tech enterprise. We offer IVD raw materials, diagnostic
reagents, and OEM service as well.
Hotgen Biotech is one of the main suppliers of IVD biological raw materials in China. The
raw materials, including recombinant antigens and monoclonal antibodies, have been
exported to North America. Our products are popular due to high quality, and little
variation between each batch.