Conventional silica based HPLC stationary phases are usually bonded with mono-type alkyl chain molecules, e.g., C18, C8, etc. Recent studies have revealed that synergistic effects can be obtained when the bonded surface consists of C18 mixed with a shorter chain such as C8, amide or nitro-phenyl, etc. These new products offer different selectivity, coordinating multi-functionality, as well as a spacer effect (C18/C8).
It is diffcult to produce a uniformly bonded C18 surface on silica due to steric hindrance of the bulky C18 chain. This problem can be easily overcome when the surface is bonded with mixed chain lengths, C18 and a shorter silane. As a result, there are many advantages: improved surface uniformity, better penetration of molecules during partitioning due to less steric hindrance, and different selectivity compared to a mono-chain type stationary phase.
As one of the leaders in separation technologies, Bonna-Agela Technologies has innovatively developed a family of non-ionic, mixed-phase HPLC/SFC columns
Optimix C18/C8:
mproved performance from a mixed-phase C18/C8 (1:1) column compared to mono-chain C18 or C8 columns
● Alternative selectivity;
● Improved selectivity for stereo isomers, better differentiation of shapes;
● Better peak shape due to uniformity of the bonding;
● Balanced hydrophilicity and hydrophobicity: extended retention for polar compounds; non-excessive retention for strong hydrophobic compounds.
Characteristics: Metal Impurity<30ppm; Pore Size:100Å; Double End-cap; Available Particle Size: 5µm
Optimix C18/Amide
A mixed-phase of C18 and propionic amide provides unique selectivity which allows extremely polar and non-polar compounds to be analyzed in a single run under isocratic conditions.
Characteristics: Metal Impurity<10ppm; Pore Size:100Å; Single End-cap;
Available Particle Size: 3µm, 5µmPerformance
Features:
● Unique selectivity
● Balanced retention for extremely polar and non-polar compounds
● Greater retention for polar compounds due to coordinating effects of C18 and amide
● Minimal tailing for basic compounds compared to any other type of columns, due to suppression of silanol effects by the amide group.
Ordering Info
Surface: 380m2, Pore Size 100Å/g |
Type | Dimension (mm) | Particle (μm) | Optimix C18/C8 | Optimix C18/SAX | Optimix C18/ Nitrophenyl | Optimix C18/SCX |
Analytical | 2.1×30 | 5 | OP950302-OC | OP950302-SA | OP950302-NP | OP950302-SC |
Analytical | 2.1×50 | 5 | OP950502-OC | OP950502-SA | OP950502-NP | OP950502-SC |
Analytical | 2.1×100 | 5 | OP951002-OC | OP951002-SA | OP951002-NP | OP951002-SC |
Analytical | 2.1×150 | 5 | OP951502-OC | OP951502-SA | OP951502-NP | OP951502-SC |
Analytical | 4.6×50 | 5 | OP950505-OC | OP950505-SA | OP950505-NP | OP950505-SC |
Analytical | 4.6×100 | 5 | OP951005-OC | OP951005-SA | OP951005-NP | OP951005-SC |
Analytical | 4.6×150 | 5 | OP951505-OC | OP951505-SA | OP951505-NP | OP951505-SC |
Analytical | 4.6×200 | 5 | OP952005-OC | OP952005-SA | OP952005-NP | OP952005-SC |
Analytical | 4.6×250 | 5 | OP952505-OC | OP952505-SA | OP952505-NP | OP952505-SC |
Guard Cartridge | 4.6×10,4/pk | 5 | OP950105-OC | OP950105-SA | OP950105-NP | OP950105-SC |
Guard Cartridge | 4.6×10,4/pk, Direct connection | 5 | OP950105-OCS | OP950105-SAS | OP950105-NPS | OP950105-SCS |
Cartridge Holder | CH-100 | <TD style="PADDING-RIGHT: 5.4pt; PADDING-LEFT: 5.4pt; BORDER-LEFT-COLOR: rgb(240,240,240); PADDING-BOTTOM: 0cm; MARGIN: 0px; WIDTH: 45.75pt; BORDER-TOP-COLOR: rgb(240,240,240); PADDING-TOP: 0cm; BORDER-BOTTOM: windowtext 1pt solid; HEIGHT: 12pt; BACKGROUND-COLOR: transparent; BORDE