Creative Biolabs offers assay services of evaluating the stability of TCR/CD3 complex to ensure the harvest of high quality TCR-modified T cells. The effective interaction of CD3 with TCR and the ξ-chain is required for the generation of activation signal in T lymphocytes. Increased stability of the TCR/CD3complex contributes to the enhanced antitumor response activity of T cells. At Creative Biolabs, the TCR/CD3 complex stability assay can be achieved via immunoprecipitation and immunoblot. Creative Biolabs offers assay services to evaluate the stability of TCR/CD3 and ensure obtain high quality TCR-modified T cells.
https://www.creative-biolabs.com/car-t/tcr-cd3-stability-assay.htm