Calcein AM is a cell-permeable dye that, upon entering live cells, is cleaved by intracellular esterases, leaving membrane-impermeant calcein, a fluorescent indicator with absorption and emission maxima of 494 and 517 nm, respectively. It can be used as an indicator of cell viability, cell-cell communication, cytotoxicity, or changes in intracellular calcium, fluoride, iron, or mercury. As calcein is a substrate for multidrug resistance-associated protein 1 (MRP1) and multidrug resistance protein 3 (MDR3, P-glycoprotein 3), calcein AM is used to study these proteins and their regulation.
Calcein AM is colourless solid, and with molecular weight is 995. Abbkine supplies below price/size for your choice: $210/1 mg, $1575/10 mg.
The Calcein AM has below features: λEX/λEm: 494/517 nm (pH 8) (calcein).
More Tracer reagent at https://www.abbkine.com/product-category/biochemical/tracer-reagent/.
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