an immunoglobulin that reacts with cytoplasmic components of all of the cells in the pancreatic islets. These antibodies occur in about 60% to 70% of newly diagnosed patients with insulin-dependent diabetes mellitus, providing strong evidence for an autoimmune origin and pathogenesis of the disease. The presence of ICA can be demonstrated for years before the occurrence of symptoms. The antibody tends to disappear with time.
Rat Islet cell antibody (ICA) ELISA Kit employs the competitive enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with an antibody specific to ICA. Standards or samples are then added to the appropriate microtiter plate wells with a Horseradish Peroxidase (HRP)-conjugated ICA and incubated. The competitive inhibition reaction is launched between with HRP labeled ICA and unlabeled ICA with the antibody. A substrate solution is added to the wells and the color develops in opposite to the amount of ICA in the sample. The color development is stopped and the intensity of the color is measured.
Rat Islet cell antibody (ICA) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/rat-islet-cell-antibody-ica-elisa-kit-kte100950/
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