Basigin is a member of the immunoglobulin superfamily, with a structure related to the putative primordial form of the family. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, basigin is thought also to play a role in intercellular recognition.It has a variety of functions. In addition to its metalloproteinase-inducing ability, basigin also regulates several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes.Basigin is a type I integral membrane receptor that has many ligands, including the cyclophilin proteins Cyp-A and CyP-B and certain integrins.
Rat Basigin (BSG) ELISA Kit employs a two-site sandwich ELISA to quantitate BSG in samples. An antibody specific for BSG has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyBSG present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for BSG is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of BSG bound in the initial step. The color development is stopped and the intensity of the color is measured.
Rat Basigin (BSG) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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