MTRR encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in MTRR can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of MTRR results in multiple transcript variants.
Rat Methionine synthase reductase (MTRR) ELISA Kit employs a two-site sandwich ELISA to quantitate MTRR in samples. An antibody specific for MTRR has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyMTRR present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MTRR is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MTRR bound in the initial step. The color development is stopped and the intensity of the color is measured.
Rat Methionine synthase reductase (MTRR) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/rat-methionine-synthase-reductase-mtrr-elisa-kit-kte100560/
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