Human Thymosin beta-4, Y-chromosomal (TMSB4Y) ELISA Kit,Abbkine_specification/price/image

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Lahn and Page (1997) isolated testis cDNAs encoding TB4Y, a Y-linked TB4X homolog. They identified TB4Y as 1 of 5 NRY genes that were expressed in many tissues and have homologs on the X chromosome that escape X inactivation.The antigen, an 11-mer peptide (EVLLRPGLHFR), was encoded by a polymorphic region 405 bp upstream of the initiation codon of TMSB4Y. CTL precursor frequency analysis showed that approximately 25% of the total donor CTL responses in the patient 50 days after transplant were directed at this epitope, and the precursor was detectable almost 2 years after transplant. RT-PCR analysis detected wide expression of TMSB4Y mRNA in normal tissues, including hematopoietic cells, and TMSB4Y was also expressed in some leukemic cells.

Human Thymosin beta-4, Y-chromosomal (TMSB4Y) ELISA Kit employs a two-site sandwich ELISA to quantitate TMSB4Y in samples. An antibody specific for TMSB4Y has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyTMSB4Y present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TMSB4Y is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TMSB4Y bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Thymosin beta-4, Y-chromosomal (TMSB4Y) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.