Human Collagen alpha-1 (VI) chain (COL6A1) ELISA Kit,Abbkine_specification/price/image

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The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively.The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.Defects in COL6A1 are a cause of Bethlem myopathy (BM).

Human Collagen alpha-1 (VI) chain (COL6A1) ELISA Kit employs a two-site sandwich ELISA to quantitate COL6A1 in samples. An antibody specific for COL6A1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyCOL6A1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for COL6A1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of COL6A1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Collagen alpha-1 (VI) chain (COL6A1) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-collagen-alpha-1-vi-chain-col6a1-elisa-kit-kte62278/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.