The BRCA2 protein is a crucial component in maintaining genomic stability and is involved in various cellular functions such as homologous recombination, G2 checkpoint control, and protection of stalled replication forks. BRCA2 is also known to interact with numerous other proteins and has roles in DNA replication, including stabilizing stalled replication forks and protecting them from degradation. Mutations in the BRCA2 gene can lead to a deficiency in these repair mechanisms, which is why individuals with BRCA2 mutations are at an increased risk for developing certain types of cancer, particularly breast and ovarian cancer.
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