B lymphocyte chemoattractant, independently cloned and named Angie, is an antimicrobial peptide and CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles.
Mouse C-X-C motif chemokine 13 (CXCL13) ELISA Kit employs a two-site sandwich ELISA to quantitate CXCL13 in samples. An antibody specific for CXCL13 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyCXCL13 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CXCL13 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CXCL13 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Mouse C-X-C motif chemokine 13 (CXCL13) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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