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Caspase-3 Mouse Monoclonal Antibody (4B8)
Caspase-3 Mouse Monoclonal Antibody (4B8)
Origin of place China
Model ABM40271
Supplier Abbkine Scientific
Price $100
Hits 143
Updated 10/16/2019
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CASP3 (caspase 3) encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of CASP3 results in two transcript variants that encode the same protein.

The Abbkine Caspase-3 Mouse Mouse Monoclonal Antibody (4B8) was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen anddetects endogenous levels of CASP3. The antibody has been validaed in IHC-P and reacts with Human, Mouse, Rat samples.

Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-Caspase-3 Mouse Monoclonal Antibody (4B8) at https://www.abbkine.com/product/caspase-3-mouse-monoclonal-antibody-4b8-abm40271.

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