Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by HDAC1 (histone deacetylase 1) belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

The Abbkine HDAC1 Mouse Mouse Monoclonal Antibody (4E1) was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen anddetects endogenous levels of HDAC1. The antibody has been validaed in IHC-P, IF and reacts with Human, Mouse, Rat samples.

Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-HDAC1 Mouse Monoclonal Antibody (4E1) at https://www.abbkine.com/product/hdac1-mouse-monoclonal-antibody-4e1-abm40270.

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.