HSPD1（heat shock protein family D (Hsp60) member 1) encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. HSPD1 is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with HSPD1. Two transcript variants encoding the same protein have been identified for HSPD1. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

The antibody detects endogenous HSP60 protein.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:1000-2000, IHC-p: 1:200-500.

HSP60 Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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