Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The catalytic portion of mitochondrial ATP synthase consists of five different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). ATP5J2 （ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2)encodes the f subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for ATP5J2. ATP5J2 has multiple pseudogenes. Naturally occurring read-through transcription also exists between ATP5J2 and the downstream pentatricopeptide repeat domain 1 (PTCD1) gene.

ATP5J2 Polyclonal Antibody detects endogenous levels of ATP5J2 protein.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.

ATP5J2 Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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