1.Details

Heparin affinity chromatography resin can be applied for separation and purification of protein molecules that have specific binding with heparin molecules, including coagulation factors, antithrombin III, growth factors, interferon and lipase.

Heparin affinity chromatography resin uses super-macro-porous polyacrylate hard gel as matrix and adopts unique chemical bonding technology from Bogen (A Duoning company) to immobilize heparin molecules, separating protein of interest through the specific binding between heparin and antithrombin III or protein molecules with similar structures.

2.Features

Case Study

Purification of antithrombin III

Column size: 1.0cm ID x 2.5cm，CV=2mL

Flow rate: 1mL/min

Sample: Pretreated genetically modified goat milk (after 0.45μm membrane filter)

1.Elution peak P1 of Bogen resin

2.Elution peak P2 of Bogen resin

3.Elution peak P1 of competitor's resin

4.Elution peak P2 of competitor's resin

3.Advantages

• High protein-binding affinity

• High protein recovery

• Large pore size with low mass transfer resistance, suitable for purification of high viscosity samples

4.Specification

Prepacked Heparin affinity chromatography column

Duoning Biotech is a leading one-stop bioprocess solutions provider from China, committed to offering products and services required for the discovery, development and commercialization production of biologics, including reagents, consumables, instruments, equipment, and services. Leveraging our integrated bioprocess system, we empower our customers to achieve effective, reliable, lower-cost and higher-quality biologics manufacturing processes.