The Tribute™ is a revolutionary new peptide synthesizer designed with your convenience in mind.  With its compact benchtop design and simple setup, the Tribute™ is perfect for the novice, while its powerful features and flexibility make it perfect for the advanced peptide chemist.  With never-before-seen features like its full-color, chemical-resistant touchscreen and unique Intellisynth UV-Monitoring and Feedback Control system, the Tribute™ will revolutionize the way you make peptides! Now with the new Infrared (IR) Heating Option!  Click on the links below to view additional Features and Specifications. 

"Our Tribute continues to work exceptionally well and we have achieved some impressive syntheses including of very complex peptides.  If all goes well with our fund raising in this difficult economic climate, we'll certainly look to purchase a second unit."

-Quote from Melbourne Laboratory, Australia

Features：

*New* Infrared (IR) Heating Option *New*
Infrared (IR) heating is the most advanced heating method on the market today!  Rapid, precise IR heating can be used to heat more than one reaction vessel at the same time, is compatible with vortex mixing for homogeneous temperature profiles, and can be scaled-up!  Unlike other systems, IR heating on the Tribute also features highly accurate temperature measurements and real-time, simultaneous temperature sensing for precise temperature control!

IntelliSynth UV-Monitoring and Feedback Control Option

The Tribute's new UV-Monitoring option allows you to monitor the extent of Fmoc removal during the deprotection reaction, and use that data to automatically adjust deprotection times and repetitions as well as coupling times.  View, print and record data in real-time.  minimize synthesis times and solvent usage as well as trial-and-error when synthesizing difficult peptides.  no solvent flow tests, nitrogen adjustments, special rinsing or special software modules needed!  Retrofit your existing Tribute with UV-Monitoring today!

 

High Efficiency Couplings
Amino acid is pre-activated in the vial by the addition of base solution. Then the active HOBt-ester is transferred to the reaction vessel and a highly efficient coupling ensues.

2 Independent Reaction Vessels
The Tribute™´s reaction vessels are completely independent.  Synthesize any 2 peptides simultaneously at different scales and using different programs for each cycle!

101 Unattended Couplings
The Tribute™´s amazingly compact amino acid rack can perform over 100 couplings without reloading!  Perfect for long peptide synthesis.
Click here for video of amino acid rack

Full-Color Chemical-Resistant Touchscreen
Completely revolutionary, this cutting-edge feature makes software operation a snap, and with no external computer, the Tribute™ saves you valuable lab space as well!
Click here for video

Flexible Fluid Delivery (Top-Down or Bottom-Up)
The Tribute™ is completely flexible.  Choose Top-Down or Bottom-Up deliveries depending on the properties of your reagent.
Click here for video

Adjustable Nitrogen and Vortex Mixing
The Tribute™ features fully adjustable nitrogen and independently adjustable vortex mixing.  Enjoy high coupling efficiencies with great mixing!

Barcode Scanning of Amino Acid Vials
Loading amino acid vials is a snap with this feature!  Just scan, load, and press the forward button!
Click here for video

User Logging
The Tribute™ provides different levels of security for different users with its login screen.  
■ System access limited to authorized individuals
■ User ID and password provide an electronic signature for each user
■ Users may login as an Administrator, Designer or Runner

Personalized User Databases
Individual users can create their own programs and peptide sequences that can only be accessed when they are logged in. Files can be created on the Tribute™ or on an external computer and transferred to the Tribute™ via a portable USB drive:

E-mail Notification Feature
Have the Tribute™ send an email to your computer or cell phone at a specified program step, at the beginning of each cycle, or when an error occurs.

Safe Response Feature
The Tribute™ can rinse and drain your reaction with a solvent of your choice if your synthesis is interrupted for any reason.

Automated Cleavage
The Tribute™ can deliver TFA to the reaction vessel from a solvent bottle or an amino acid vial.  Afterwards, collect your cleaved peptide in a 50 mL centrifuge vial in the Tribute™´s convenient collection stand.  Just add ether directly to the collection vial and centrifuge to precipitate your peptide!

Automated Cycle Dependent Volume Incrementation
The Tribute™ can automatically adjust delivery volumes to account for resin volume increases as your synthesis progresses.  Delivery volumes will increase by an increment of your choice each cycle.

Specifications：

Synthesis Scale:	0.005 - 2.0 mmol (up to 2.1 g of resin per RV)
Reaction Vessels:	2 (10 mL, 45 mL)
Chemistry:	Solid phase synthesis (e.g. peptide, peptoid, PNA, DNA, combinatorial, small organic molecules)
Activation Schemes:	In-situ; experimental
Reagents/Solvents:	5 pressurized solvents (1 to 4 L each) 101 position amino acid rack, barcode scanning of amino acid vials
Fluid Measurement:	Fixed loop measurement with optical sensors
Solution Transfer:	Nitrogen or Argon pressure. Top down or bottom-up deliveries.
Solution Removal:	Filtration
Waste Container:	(20 L) with float switch
Agitation:	Nitrogen bubbling and vortex mixing - adjustable
Interface:	Proprietary Tribute control software, internal CPU, full-color chemical-resistant touchscreen
Power:	115/230 volts, 50/60 Hz
Dimensions:	43 inch Wide x 23.2 inch Height x 25.4 inch Depth (109 cm W x 59 cm H x 64 cm D)
Weight:	Approximately 100 lbs. (45 kg)
Warranty:	One year, parts and labor
Additional Features:	Automated Cycle Dependent Volume Incrementation Safe Response Feature
Optional:	User Workstation Utility E-mail Notification Cleave/Collect Assembly

Protein Technologies, Inc. (PTI) was founded in 1985 by researchers affiliated with the University of Arizona in Tucson. In 1990, we launched our first peptide synthesizer, the PS3™, and since then we have manufactured and sold the world's finest solid phase synthesizers.

The PS3™ peptide synthesizer met with immediate success and continues to be one of the most reliable, cost effective, and easy to use instruments on the market today.

In 1993 we introduced the Symphony®, a fully automated peptide synthesizer featuring 12 independent reaction vessels that has dominated the multi-channel solid-phase synthesis market. The Symphony® is ideal for custom peptide synthesis because individual reaction vessels may be started, paused, or stopped regardless of what the other reaction vessels are doing, making it equivalent to 12 separate synthesizers in one! The Symphony® is widely regarded as perhaps the finest synthesizer available, and there are hundreds of Symphonys®operating worldwide.


In 1996 we introduced the Sonata®, a large scale automated peptide synthesizer. We included the well-established fluid movement of the Symphony®, as well as its ease of use, reagent optimization, and automated cleavage. We also added a mechanical agitator to assist nitrogen bubbling in order to efficiently mix large amounts of resin in the larger reaction vessels. The Sonata® can produce from grams to near-kilograms of expected product. In 2009, we introduced the Sonata® XT which doubles the capacity of the original Sonata® peptide synthesizer!


In 2000 we introduced the Quartet™, a 4 channel version of the Symphony® peptide synthesizer. It has all of the advantages of the Symphony® and it can be upgraded to the full Symphony® if the user's needs should grow.


In 2006, we introduced the Prelude®, a 6-channel parallel peptide synthesizer that features no-prime deliveries and extra amino acid bottles for expensive monomer additions. It can also rinse your reaction when an error occurs and send an E-mail status report to your computer or cell phone.

In 2007, we introduced the Tribute®, a revolutionary 2-channel parallel peptide synthesizer featuring a full-color chemical-resistant touchscreen, a 101-position amino acid vial rack, amino acid barcode scanning, fully-adjustable vortex and nitrogen mixing, as well as individual user logging. It also features E-mail notification and washing on error like the Prelude®. In 2009, we added the unique IntelliSynth™ UV-Monitoring and Feedback Control System to the Tribute® peptide synthesizer, which is the only UV-Monitoring system that monitors during the deprotection reaction, so it can control both the deprotection time as well as the number of repeats. In 2012, we added infrared (IR) heating to the Tribute®, giving it the fastest time to temperature of any heating technology on the market today! In addition, unlike other rapid heating methods, infrared heating can be performed on more than one reaction vessel at once, and is compatible with vortex mixing, so you can be sure you have an even temperature profile throughout your reaction vessel. Other heated systems that rely on nitrogen mixing may have hot and cold spots, which could compromise the consistency of your chemistry.

In 2010, we introduced the Overture™ robotic peptide library synthesizer. The Overture™ is the most flexible robotic platform on the market today. In addition to powerful library generation tools, the Overture™ is the only robotic platform that supports multiple, simultaneous protocols, the synthesis of different scales at the same time, and on-board automated cleavage without user intervention!

In 2012, we introduced the Symphony® X. With twice the number of reaction vessels as the original Symphony®, the Symphony® X can synthesize up to 12 peptides using preactivation or up to 24 peptides using in situ activation! It also features up to 40 amino acid positions, no-prime deliveries for expensive reagent additions, infrared heating, UV-monitoring, E-mail notification and more! With its 12 independent reactor pairs, the Symphony® X is the perfect instrument for peptide production or protocol optimization.


We have built our company on the belief that our products must be the highest possible quality, and we support our products with a dedicated field service team. We are proud of our reputation for reliability and value the trust our customers and partners have placed in PTI. Today we continue to grow and innovate to serve the needs of the peptide synthesis community.