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Home >Products> Reagents >Antibody> PRDM1/Blimp1 Recombinant Rabbit mAb (S-1972-3)
PRDM1/Blimp1 Recombinant Rabbit mAb (S-1972-3)
PRDM1/Blimp1 Recombinant Rabbit mAb (S-1972-3)
Origin of place Singapore
Model S0B6058-25μl
Supplier ANT BIO PTE.LTD.
Price 100
Hits 10
Updated 9/1/2025
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Product Specification


HostRabbit
AntigenPRDM1/Blimp1
SynonymsPR domain zinc finger protein 1; BLIMP-1; Beta-interferon gene positive regulatory domain I-binding factor; PR domain-containing protein 1; Positive regulatory domain I-binding factor 1 (PRDI-BF1; PRDI-binding factor 1)
ImmunogenSynthetic Peptide
LocationCytoplasm, Nucleus
AccessionO75626
Clone NumberS-1972-3
Antibody TypeRecombinant mAb
IsotypeIgG
ApplicationWB, IHC-P, ICC
ReactivityHu, Ms, Rt
Positive SampleTHP-1, HeLa, A431, RAW264.7, rat colon
PurificationProtein A
Concentration0.5 mg/ml
ConjugationUnconjugated
Physical AppearanceLiquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 掳C as supplied

Dilution


applicationdilutionspecies
WB1:1000Hu, Ms, Rt
IHC-P1:1000Hu, Ms, Rt
ICC1:500Hu, Ms

Background

PRDM1, also known as Blimp1, is a crucial transcriptional regulator that plays significant roles in various biological processes. It is a zinc finger protein with a complex structure containing multiple functional domains. In the immune system, PRDM1/Blimp1 is essential for the terminal differentiation of B cells into plasma cells, helping to suppress the expression of genes related to B cell proliferation and maintenance of the B cell phenotype, thereby facilitating the transition to plasma cells which are specialized for antibody production. Additionally, it also has important functions in other cell types and developmental contexts, such as influencing the differentiation of certain T cell subsets and participating in the regulation of some developmental processes in tissues like the skin. Its dysregulation has been implicated in various diseases, including certain types of cancers and autoimmune disorders, making it an interesting target for potential therapeutic interventions.

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