INT TFF tangential flow filtration system
The INT TFF tangential flow filtration system is used for the separation and purification of monoclonal antibodies, vaccines, plasma, and therapeutic proteins. It is highly suitable for experimental and production scale applications, supporting rapid scaling operations from small to large scale.
The system is divided into two series: manual and automatic. Manual is convenient and easy to operate for users
Automatic can achieve fully automatic control of tanks, detectors, and pumps
This system has a very low retention volume to achieve maximum volume concentration and optimal product recovery, thereby improving process performance.
Product characteristics
The modular standard options allow for unique system configurations that best meet process requirements while minimizing upfront investment.
The full process automation makes it easier to achieve cGMP standards for consistent production of high-value drugs at both preclinical and clinical scales.
Design optimization and component integration result in minimal dead volume and ensure maximum product recovery rate.
The design of feeding batch, concentration, full cycle or single channel mode maximizes the performance of TFF.
High sensitivity online detector, available in pressure, UV pH、 Various detectors such as conductivity
The software platform complies with FDA 21 CFR Part 11 regulations, is easy to operate, has an intuitive user interface, user-defined processes, and alarm setpoints
Ergonomic structural design, easy to operate and maintain
Comprehensive services ensure the rapid implementation and performance optimization of equipment.
Highly customized based on INT TFF membrane filtration system, products can be customized according to customer requirements.

Selection Table for Tangential Flow Filtration System

System type	Manual tangential flow filtration system	Automatic tangential flow filtration system
Membrane type	Optional hollow fiber, ultrafiltration membrane pack, ceramic membrane, nanofiltration membrane
Membrane area range	0.5-80㎡
Type of feed pump	Optional: peristaltic pump, diaphragm pump, rotary pump
pressure	pressure gauge	Pressure sensor
flowmeter	optional
conductance	optional
PH	Optional: PH1-14
UV detection	optional
Integrity testing	optional
prefilter	optional
CIP cleaning	optional
SIP sterilization	optional
Ultrafiltration tank	optional
Feeding pump	Optional: peristaltic pump, diaphragm pump, rotary pump
Membrane packaging fixture	Optional: 0.5 square meters (can hold 1-5 or 1-10 pieces), 2.5 square meters (can hold 1-5 or 1-10 pieces)

Suzhou COSTONES Instruments Co., Ltd. (COSTONES) is an instrument company focusing
on separation and purification. It is an equipment supplier and service provider
for biopharmaceutical, cell therapy and gene testing. It is committed to providing
users with industry-leading technical support and services.
The company has a perfect service system and executive power. It interprets the
user experience from the four aspects of technical communication, scheme design,
technical support and after-sales service, and tries to achieve seamless connection
in every link until it is recognized by customers.
For a long time, we have maintained good cooperative relations with domestic and
foreign suppliers. The main products include protein purification system,
compressible chromatographic column, ultrafiltration system, chromatographic
ultrafiltration accessories, etc., and provide maintenance services and customized
product services;
At present, Suzhou quarrying has provided high-quality services for
biopharmaceutical, cell therapy, research institutes and scientific research users.
It has carried out in-depth cooperation with customers and become a reliable partner
for customers to achieve win-win results.
We take quality first as the standard, quickly respond to customer needs, help
customers solve problems, improve efficiency, and take improving core
competitiveness for customers as our service tenet. We are willing to realize our
own value while creating value for customers and society through our unremitting
efforts.