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Protein purification system PROPS series
Protein purification system PROPS series
Origin of place China
Model
Supplier SUZHOU COSTONE INSTRUMENT CO., LTD.
Price
Hits 49
Updated 4/26/2025
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Protein purification system PROPS series

Main application fields:
Protein purification system is mainly used in biopharmaceutical fields such as monoclonal antibodies, recombinant proteins, vaccines, biological products, antibiotics, natural products and polysaccharides.
It is used for downstream process separation and purification of biological products.
Product advantages
Modular design, providing multiple configurations to meet the needs of special process flow
The high-precision double plunger infusion pump with a number of patented technologies ensures excellent separation reproducibility;
– the place where the whole system is in contact with the liquid is composed of biocompatible materials and meets the requirements of FDA, uspvi and other relevant regulations;
– dad full spectrum direct reading detector avoids the instability and high failure rate caused by the traditional mechanical switching detector;
– the fixed wavelength detector lamp is a long-life LED lamp, with a service life of more than 8000 hours, reducing the maintenance cost;
– patented UV detector flow cell, low dead volume, low peak expansion, and improved chromatographic resolution;
– high sensitivity online pH, conductivity, UV detector, low dead volume, low peak expansion, and improved chromatographic resolution;
– automatic components such as buffer selector valve, automatic sample injection valve and column position valve are centralized to improve the automation of purification;
– it has the functions of pre column, post column, differential pressure alarm and bubble sensor detection, which greatly protects the safety of the system and chromatographic column;
– the chromatography workstation software meets the requirements of fda21cfr, Part11 / GLP / GMP
Model PROPS 25 PROPS 100 PROPS150 PROPS 300
Velocity range 0.001-25ml/min 0.001-100ml/min 0.001-150ml/min 1-300ml/min
Velocity accuracy ±1.2% ±1.2% ±1.2% ±2%
Maximum withstand voltage 27.5Mpa 10Mpa 5Mpa 3.5Mpa
 
mixer
Mixing principle: dynamic mixing
Volume of mixing tank: 0.6ml, 2ml, 5ml or 15ml
Gradient accuracy: ± 0.5% (condition: 5-95%, flow rate above 2% of full scale)
valve
Type diaphragm valve or selector valve
8 valve inlets (maximum)
Including: inlet valve, injection valve, column position valve and outlet valve
Inlet valve
Inleta: 1, 2 or 10
Inletb: 1, 2 or 10
Column position valve: single column position, 5 column position or 9 column position
Outlet valve: 1 or 9
UV detector
Detector type: LED fixed wavelength or dad full spectrum read only
Number of wavelengths: 1, 2, 4 or full band
Wavelength range:
DF1: 280260 or 254nm (other calls)
Dad402: 200-400nm, any two wavelengths output (software setting)
Dad604: 200-600nm, any four wavelengths output (software setting)
Dad604: 200-800nm, any four wavelengths output (software setting)
Circulation tank:
Optical path 2mm, 2ul dead volume
Optical path 5mm, 6ul dead volume
Optical path 10mm, 8ul dead volume
PH & conductivity detector ptc01
Read range:
0.001-999.999ms/cm (conductivity), 0-14 (PH)
Accuracy: conductivity: ± 0.02ms/cm or 2% (within 0.3 to 300ms / cm)
PH: ± 0.1ph (in the range of 2-12)
Maximum pressure
5MPa (conductivity) / 0.5MPa (PH)
Flow cell volume: 20ul
Temperature range: 0-100 degrees
Temperature accuracy: ± 0.5 (within 4-45 degrees)
Collector type: open type (frac-02), closed type (frac-02p), refrigeration type (frac-02c)
Collector frac-02
Collection rack: 2
Maximum collection number: 384 (4 96 well plates)
Collection rack type: 1.5ml, 3ml, 5ml, 8ml, 15ml or 50ml
Collection volume: 0.1-50ml
Collector delay volume:
800ul (autopure100 standard, UV flow cell - collection end),
420ul (autopure25 standard, UV flow cell - collection end),
*The delay volume may change depending on the choice of configuration.
Bubble sensor:
Principle: ultrasonic, non-contact detection
Maximum quantity: 3, sample injection test, pump a test, pump B test or customized
Optional configuration
AirS01-H Bubble sensor for monitoring sample loading
CPV02RX Column position valve, supporting forward / reverse / bypass
CPV03RX 3 column position valve, supporting forward / reverse / bypass
CPV03RX*2 6 column position valve, supporting forward / reverse / bypass
MSV04 Mobile phase selection module, 4 channels
MSV10 Mobile phase selection module, 10 channels
DAD-UV 260nm or 280nm fixed wavelength
260nm and 280nm fixed dual wavelength
200-400nm arbitrary dual wavelength
DAD604 200-600 nm, Dad detector, four channels
DAD804 200-800nm, Dad detector, four channels
pH detector PH detector, 0-14 (best for ph2-12), temperature compensation, dead volume of flow cell: 88ul
OV02 Outlet valve (large volume collection valve), 1 collection channels, 1 waste liquid.
OV10 Outlet valve (large volume collection valve), 9 collection channels, 1 waste liquid.
SP25/100/300 Sample pump sSP25/100/300
0.01-25ml/min,
Velocity accuracy: 1.2%/1.2%/1.5%
Maximum pressure 27.5mpa/10Mpa/3.5Mpa
SIV-09 Sample inlet valve, 10 channels
9 sample inlets and 1 buffer inlet
PCP02 Column front and column rear pressure monitoring module
PCP01 Pre column pressure monitoring module
Frac-02 Component collector, supporting 2 collection racks
1. 3 x 7, 30mm, 21 pipes, 2 Nos
2. 5 x 12, 16mm, 60 tubes, 2 Nos
3、6 × 15, 13mm, 90 pipe, 2
4. 96 hole plate, 4
Frac-02P Closed design to avoid sample contamination
Component collector, supporting 2 collection racks
1. 3 x 7, 30mm, 21 pipes, 2 Nos
2. 5 x 12, 16mm, 60 tubes, 2 Nos
3、6 × 15, 13mm, 90 pipe, 2
4. 96 hole plate, 4
Frac-02C Closed design to avoid sample contamination
Independent refrigeration temperature control, temperature control range 4-20 ° C, error ± 1.5 ℃
Component collector, supporting 2 collection racks
1. 3 x 7, 30mm, 21 pipes, 2 Nos
2. 5 x 12, 16mm, 60 tubes, 2 Nos
3、6 × 15, 13mm, 90 pipe, 2
4. 96 hole plate, 4
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