PharmaLegacy Laboratories (Shanghai) Co., Ltd is a professional supplier which provides a variety of Osteoarthritis Model, to provide customers withGood faith managementOsteoarthritis Model ,CDX Modeland Osteoarthritis Model and so on. Since the company had been established in Building 7, 388 Jialilue Road Zhangjiang High-Tech Park Pudong District Shanghai,Pudongxin District,City area,Shanghai,China, adhere to people-oriented ,and the quality of survival, to the credibility of development,our company have made an outstanding achievement.

   The advantage of PharmaLegacyHumanized mouse modelis that it can provide more professional and thoughtful solutions timely and accurately according to the actual needs of customers.At the same time, Our company follow the latest developments on Business services,Medical service,Medical insurance, and establish long and steady partnership relation with many well-known enterprises in the same industry , to provide customers with the most professional, advanced AutoimmuneDiseasesModelx2a38631n.Details:Osteoarthritis model (OA) is a prevalent musculoskeletal disease that results in pain and low quality of life for patients, as well as enormous medical and socioeconomic burdens. The molecular mechanisms responsible for the initiation and progression of Osteoarthritis models are still poorly understood. As such, osteoarthritis model of mouse is having increasingly important roles in Osteoarthritis model research owing to the advancements of microsurgical techniques and the use of genetically modified mice, as well as the development of novel assessment tools. Osteoarthritis model, known as degenerative joint disease, involves both articular cartilage and subchondral bone. The progression of the diseased joint includes articular cartilage fibrillation, fissure and partial erosion, full thickness loss of articular cartilage and ends with bone exposed, and sclerosis of subchondral bone. Symptoms include joint pain, swelling and reduced motion in angle and extent. It can occur in any joint, but usually it affects hands, knees, hips or spine. A variety of causes – hereditary, developmental, metabolic, and mechanical – may initiate processes leading to loss of cartilage. Osteoarthritis model is the most common form of arthritis, and the leading cause of chronic disability. It affects about 40 million people in the United States.

   

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PharmaLegacy Laboratories is a leading speciality pharmacology Contract Research Organization located in Shanghai Zhangjiang High-Tech Park, China. PharmaLegacy is equipped with a world-class facility, working to international pharmaceutical industrial standards. PharmaLegacy provides preclinical in vivo pharmacology efficacy services as well a therapeutic antibody discovery service program. Our state-of-the-art platforms include:· Pioneering work using CD34+ humanized mice that carry a human immune system, to test biologics for immuno-oncology therapeutic efficacy· An NHP platform for therapeutic biologics testing in a variety of immune diseases · An advanced antibody discovery platform based on single B cell antibody sequencing · An internationally recognized Bone/Orthopaedics platform to test both hard tissue disease therapeutic candidates and medical devicesPharmaLegacy offers a full range of preclinical pharmacology services for evaluating pharmacological effects of drug candidates in the areas of inflammation/auto-Immune diseases, lung injury, liver/metabolic diseases and oncology. Our NHP platform and CD34+ humanized mice models have helped dozens of clients with IND filings