Penn-Century MicroSprayer® Aerosolizer - Model IA-1C （liquid）
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part number
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model
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description
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MSA-250
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MicroSprayer® Aerosolizer and FMJ-250 High-Pressure Syringe Assembly （Suitable for mouse and larger species）
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Penn-Century MicroSprayer® Syringe Assembly. Includes one standard MicroSprayer® Aerosolizer - Model IA-1C and one FMJ-250 High-Pressure Syringe （required for operation of the MicroSprayer® Model IA-1C）. Standard sizes for mouse （1-1/4"） or for rat （2"） （Please specify）. Both MicroSprayer® and syringe are autoclavable. Each device includes a set of five 25-µl stops and five 50-µl stops for precise dosing of smaller quantities.
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MSA-250-M
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For Mouse
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Standard size for mouse （1.25" after 120-degree bend）
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MSA-250-R
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For Rat
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Standard size for rat: （2" after 120-degree bend）
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MSA-250-C
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Custom Length
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Penn-Century MicroSprayer®/Syringe Assembly. Includes one custom length MicroSprayer® Aerosolizer - Model IA-1C and one FMJ-250 High-Pressure Syringe （required for operation of the Model IA-1C）. MicroSprayer® Aerosolizer can be made to any length or configuration （e.g. short, long, with or without standard 120-degree bend）, as specified by customer. Long lengths may be used with an endotracheal tube or bronchoscope.
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MSA-50
NEW!
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MicroSprayer® Aerosolizer and FMJ-50 High-Pressure Syringe Assembly （Suitable for mouse and larger species）
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Penn-Century MicroSprayer® Syringe Assembly. Includes one standard MicroSprayer® Aerosolizer - Model IA-1C and one FMJ-50 High-Pressure Syringe （new product for administration of up to five 10-µl doses） required for operation of the MicroSprayer® Model IA-1C. Standard sizes for mouse （1-1/4"） or for rat （2"） （Please specify）. Both MicroSprayer® and syringe are autoclavable.
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MSA-50-M
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For Mouse
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Standard size for mouse （1.25" after 120-degree bend）
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MSA-50-R
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For Rat
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Standard size for rat: （2" after 120-degree bend）
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MSA-50-C
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Custom Length
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Penn-Century MicroSprayer®/Syringe Assembly. Includes one custom length MicroSprayer®Aerosolizer - Model IA-1C and one FMJ-50 High-Pressure Syringe （required for operation of the Model IA-1C）. Each device includes a set of five 10-µl stops for precise dosing of smaller quantities. MicroSprayer® Aerosolizer can be made to any length or configuration （e.g. short, long, with or without standard 120-degree bend）, as specified by customer. Long lengths may be used with an endotracheal tube or bronchoscope.
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Model IA-1C
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Additional MicroSprayer® Aerosolizers - Standard （Suitable for mice and all larger species.）
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With 23-gauge, stainless steel delivery tube, o.d. of 025" （.64 mm）. NOTE: Must be operated with FMJ-250 High-Pressure Syringe. Standard sizes: 1-1/4" for mouse and 2" for rat after 120-degree bend. Fully autoclavable.
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IA-1C-M
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For Mouse
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Standard size for mouse （1.25" after 120-degree bend）
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IA-1C-R
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For Rat
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Standard size for rat: （2" after 120-degree bend）
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IA-1C-C
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Custom Length
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Custom sizes: any length or configuration （e.g. short, long, with or without standard 120-degree bend）, as specified by customer. Long lengths may be used with an endotracheal tube or bronchoscope. Operated with FMJ-250 High-Pressure Syringe.
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Penn-Century High-Pressure Syringes
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part number
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model
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description
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FMJ-250
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Additional FMJ-250 High-Pressure Syringe
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Manually-operated, high-pressure syringe required for operating MicroSprayer® Aerosolizer - Model IA-1C. Operates at 3000 psi. Stainless steel construction with glass insert, 250 µl capacity. Replaceable plunger with Teflon® tip. Each device includes a set of five 25-µl stops and five 50-µl stops for precise dosing of smaller quantities. Fully autoclavable.
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PLU-250
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Replacement Plunger for FMJ-250
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Replacement plunger for FMJ-250 High Pressure Syringe - with anodized aluminum thumb button and Teflon® tip.
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FMJ-50
NEW!
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Additional FMJ-50 High-Pressure Syringe （for precise administration of up to five 10-µl doses）
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New low-dose model. Manually-operated, high-pressure syringe required for operating MicroSprayer® Aerosolizer - Model IA-1C. Operates at 3000 psi. Stainless steel construction with glass insert, 50 µl capacity. Replaceable plunger with Teflon® tip. Each device includes a set of five 10-µl stops for precise dosing of smaller quantities. Fully autoclavable.
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CBA
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Custom Bronchoscopic Adaptor
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NOTE: Longer, straight custom lengths of MicroSprayer® Aerosolizers - Model IA-1C can be ordered for insertion into the working channel of a bronchoscope for administration to a lobe of the lung. Depending on the configuration of the instrument port of the bronchoscope, an adaptor may be required to stabilize the FMJ-250 High Pressure Syringe and prevent bending of the MicroSprayer® during insertion and removal. The adapter must be custom fitted to your equipment in our shop. Please contact us for details.
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Penn-Century MicroSprayers® （liquid） - Model IA-1B
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part number
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model
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description
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Model IA-1B
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MicroSprayer® Aerosolizer with 1 ml disposable polycarbonate syringe （Suitable for rat and all larger species）
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Made with stainless steel 19-gauge delivery tube that measures .048" （1.2 mm） at the very tip. Luer hub. Operates with 1-ml polycarbonate syringe （provided）, or any commercially available 1-ml polycarbonate, or 0.5 ml glass, gas-tight syringe. Fully autoclavable.
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IA-1B-R
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For Rat
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Standard size for rat: （2" after 120-degree bend）
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IA-1B-GP
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For Guinea Pig
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Standard size for guinea pig （3" after 120-degree bend）
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IA-1B-C
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Custom Length
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Custom length MicroSprayer® Aerosolizers are available in any length or configuration （short, long, with or without standard 120-degree bend）. May also be used via an endotracheal tube. Specify dimensions.
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Penn-Century Dry Powder Insufflators™
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part number
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model
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description
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Model DP-4
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Dry Powder Insufflator™ with disposable 3 ml air syringe
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Made of chemically resistant PEEK™ construction, silicone rubber valves, and hollow stainless steel delivery tube for precise administration of dry powders. Accepts all powder sizes. Air supply: 3 ml disposable air syringe （included）. Standard sizes available for intratracheal administration to rat （2"） or guinea pig （3"）.
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DP-4-R
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For Rat
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Standard size for rat: （2" after 120-degree bend）
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DP-4-GP
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For Guinea Pig
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Standard size for guinea pig （3" after 120-degree bend）
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DP-4-C
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Custom length
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Custom size DP-4 with delivery tube: any length or configuration （straight or with standard 120-degree bend）, as specified by customer.
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DP-EXT-R
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For Rat
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Extra delivery tube for DP-4 for Rat
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DP-EXT-GP
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For Guinea Pig
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Extra delivery tube for DP-4 for Guinea Pig
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DP-EXT-C
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Custom length
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Custom length tips for the Penn-Century Dry Powder Insufflator™ - Model DP-4 may be ordered in any length, straight or with a 120-degree bend, or with custom, flexible delivery tube options. Longer lengths may be inserted into an endotracheal tube or bronchoscope. （Specify dimensions）
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SC-X
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Sample Chamber Extension
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100 mg Sample Chamber Extension - attaches to Model DP-4 for administration of large doses
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DPM-APA
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Penn-Century Dry Powder Insufflator™/Air Pump Assembly for Mouse
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The only light, purely mechanical, manually operated method for intratracheal administration of dry powders to mouse. Includes （1） Penn-Century Dry Powder Insufflator™ for Mouse and （1） Penn-Century Air Pump with adjustable air volume setting （set for mouse at 200 µl）. Insufflator made of chemically resistant PEEK™ construction with removable stainless steel delivery tube sized for intratracheal administration of dry powders to mouse. Operates with spring-loaded, Penn-Century Air Pump for easy, rapid administration of 200 µl pulses of air.
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Model DP-4M
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Additional DP-4M Dry Powder Insufflator™ for Mouse
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Dry Powder Insufflator™ with valve assembly for mouse. PEEK™ construction with silicone rubber valving. Can be used with any animal, including mouse, depending upon delivery tube dimensions. Comes with 23-gauge delivery tube （1.25" after the 120-degree bend）. Operates with spring-loaded, Penn-Century Air Pump for easy, rapid administration of 200 µl pulses of air.
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DPM-EXT
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Extra delivery tube
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Extra delivery tube for DP-4M for Mouse
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Penn-Century accessories for precise intratracheal aerosol administration
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part number
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model
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description
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AP-1
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Air Pump
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Hand-held precision air pipette with spring-loaded thumb button for easy, fast administration of air pulses. Attaches to any size Penn-Century Dry Powder Insufflator™. Plastic construction with rubber square-ring seal. Outlet: male luer slip. Adjustable air volume setting: 0 - 5 ml. Required for use with DP-4M in mice. Recommended for use in rat, or in other applications requiring rapid dosing of multiple subjects with minimal hand motion. Specify animal to be used.
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LS-2
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Small-Animal Laryngoscope
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Designed to clearly illuminate the trachea and epiglottis for intubation and insertion of a Penn-Century MicroSprayer® or Dry Powder Insufflator™. Now with a fiberoptic LED light source for clear, bright illumination. Each device comes with a custom-made small, tapered stainless steel blade for moving aside the animal's tongue. （Specify animal when ordering）. New easy-grip handle with curved ergonomic shape fits securely in the palm of the hand. Coated with non-slip Santoprene™ rubber. Operates with one 3-volt lithium battery （included）. Autoclavable.
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LS-2-M
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For Mouse
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With blade sized for use in Mouse
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LS-2-R
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For Rat
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With blade sized for use in Rat
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LS-2-GP
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For Guinea Pig
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With blade sized for use in Guinea Pig
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LS-2-C
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For larger species
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Custom blade for larger species. Please specify when ordering.
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MIP
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Mouse Intubation Platform
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For safe, rapid, easy intratracheal intubation of mice. Adjustable posts for stabilizing anesthestized animal. Unique swiveling neck support permits clearer visualization and access to trachea. Made of sterilizable Plexiglass®/Perspex® with stainless steel and Delrin® fittings. Can be attached to any standard lab clamp stand （not included.） NOTE: $50 discount is offered when Platform is purchased with any Penn-Century MicroSprayer® or Dry Powder Insufflator™.
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1, Liquid PenWu Device
PenWu Device for Mouse Cat.No.：BJ-PW-M
PenWu Device for Rat Cat.No.：BJ-PW-R
PenWu Device for (Custom) Cat.No.：BJ-PW-C
Whole set picture: Mini. Quantitative unit is 5ul，Total volume: 250ul, 500ul, 1ml, volume can be selected, default is 250ul.
2,Tip for Mouse Cat.No.：BJ-PW-M-T, Tip for Rat Cat.No.：BJ-PW-R-T
Tips: We can made in specified length
3,Quantitative Column: Two specification in 25ul and 50ul
4,Injection Rod: pls use the plastic at bottom part to stick the liquor before use to increase lubrication.
5,Main part of the injection syringe : the material is glass in transparency, there have scale on it , one scale is 5ul.
When using it, push hard and fast, and the faster the better.
PenWu Device for Dry Powde（Mouse） Cat.No.：BJ-PW-FM-M
PenWu Device for Dry Powde（Rat） Cat.No.：BJ-PW-FM-R
PenWu Device for Dry Powde（Custom） Cat.No.：BJ-PW-FM-C
Dry Powder Insufflato with disposable 5 ml& 2.5ml air syringe Made construction, silicone rubber valves, and hollow stainless steel delivery tube for precise administration of dry powders.. Standard sizes available for intratracheal administration to Mouse(1.25"),Rat (2") or Guinea pig(3"). Can be customized for use by other large animals.
Description: For fast, precise, targeted administration of a “cloud” of dry powder. Device made of Stainless steel material and silicone valves. Standard delivery tube made of rigid, hollow stainless steel tubing with rounded tip. Single dose range: 1-5mg (To be loaded with only one dose at a time) For larger single doses: 100mg Sample Chamber Extension may be attached for larger doses. Operates with: Commercial 2.5ml&5ml plastic air syringe (provided). Particle size range: Dry Powder can be loaded with dry powders in a very wide range of sizes from nanoparticles to large macroparticles. Device does not filter or affect powders traveling through it. Delivery tube: Stainless steel with rounded tip. Rat:Outer diameter 1 mm, Inner diameter 0.7mm. Mouse:Outer diameter 0.7mm,Inner diameter 0.4mm. (Hollow throughout) Custom delivery tubes. Available in stainless steel - straight or with bend, or in flexible plastic tubing. Longer lengths may be inserted directly, or via an endotracheal tube or bronchoscope in larger species. Reusable/Sterilizable: Stainless steel tip detachable and autoclavable.
7,Small-Animal Laryngoscope
Cat.No.：BJ-L
Use battery Number 5
Designed to clearly illuminate the trachea and epiglottis for intubation and insertion.Now with a fiberoptic LED light source for clear, bright illumination. Each device comes with a custom-made small,tapered stainless steel blade for moving aside the animal's tongue.Use battery Number 5。For Mouse,With blade sized for use in Mouse, For Rat, With blade sized for use in Rat BJ-L-C, Custom blade for larger species. Please specify when ordering.
8, Mouse or Rat Intubation Platform MIP
Cat.No.：BJ-P-M Cat.No.：BJ-P-R
For safe, rapid, easy intratracheal intubation of mice. Adjustable posts for stabilizing anesthestized animal. Unique swiveling neck support permits clearer visualization and access to trachea.
9,Patent Certificate
Liquid PenWu Device Paper（Liquid）：Some schools and research institutes have published papers after using our products, which cite our product number or company name or product name.
Paper FOR PenWu Device
You can search in these papers: BJ-PW-M & BJ-PW-R & BJ-PW-FM-M & BJ-PW-FM-R & Bio Jane & PenWu Device for Mouse & PenWu Device for Rat and so on. These papers will show that.
The total impact factor is over 400.
Paper（Liquid）：
1.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.202007557
Nanoparticle-Mediated Delivery of Inhaled Immunotherapeutics for Treating Lung Metastasis
2.
https://www.pnas.org/doi/full/10.1073/pnas.2102957118
Inhalable nanocatchers for SARS-CoV-2 inhibition
3.
https://pubs.acs.org/doi/10.1021/jacs.1c08017
Renal-Clearable Molecular Probe for Near-Infrared Fluorescence Imaging and Urinalysis of SARS-CoV-2
4.
https://www.nature.com/articles/s41401-021-00808-z
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
5.
https://www.nature.com/articles/s41401-021-00618-3
Roxithromycin attenuates bleomycin-induced pulmonary fibrosis by targeting senescent cells
6.
https://www.sciencedirect.com/science/article/pii/S1742706122003634
ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment
7.
https://doi.org/10.1007/s12274-021-4012-9
A chitosan-mediated inhalable nanovaccine against SARS-CoV-2
8.
https://journals.physiology.org/doi/full/10.1152/ajplung.00560.2020
p55PIK deficiency and its NH2-terminal derivative inhibit inflammation and emphysema in COPD mouse model
9.
https://doi.org/10.1002/btm2.10280
Macrophage-targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis
10.
https://doi.org/10.1183/13993003.03697-2020
The methyl-CpG-binding domain 2 facilitates pulmonary fibrosis by orchestrating fibroblast to myofibroblast differentiation
11.
https://www.hindawi.com/journals/omcl/2022/9300269/ (2022)
MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema
12.
https://www.sciencedirect.com/science/article/pii/S2666386422005641 (2023.1)
A cytoderm metabolic labeling AIEgen for rapid detection and intracellular ablation of Mycobacterium tuberculosis
13.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115697/ (2022.5)
Macrophage‐targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis
14.
https://pubs.acs.org/doi/full/10.1021/acsnano.3c00906 （2023.4）
A Multifunctional Nanoparticle Mitigating Cytokine Storm by Scavenging Multiple Inflammatory Mediators of Sepsis
15.
https://onlinelibrary.wiley.com/doi/10.1002/smll.202300545 （2023.4）
Inhaled Lipid Nanoparticles Alleviate Established Pulmonary Fibrosis
16.
https://www.sciengine.com/SCLS/doi/10.1007/s11427-022-2314-8;JSESSIONID=63cbf8c9-4345-4b3b-92ba-0efe5f8c34d4 （2023.4）
Local administration of liposomal-based Plekhf1 gene therapy attenuates pulmonary fibrosis by modulating macrophage polarization
17.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759842/
MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema
18.
https://doi.org/10.1016/j.biomaterials.2023.122283
Inhalable pH-responsive DNA tetrahedron nanoplatform for boosting anti-tumor immune responses against metastatic lung cancer
19.
https://doi.org/10.1021/acsnano.3c08660 （2023.12）
Inhalable Bottlebrush Polymer Bioconjugates as Vectors for Efficient Pulmonary Delivery of Oligonucleotides
20.
https://doi.org/10.3390/pharmaceutics15071951 Pharmaceutics 2023,
15(7), 1951;
Systemic Protein Delivery via Inhalable Liposomes: Formulation and Pharmacokinetics
21．
https://www.nature.com/articles/s41467-024-50312-1 (2024.7)
Inhalable cardiac targeting peptide modified nanomedicine prevents pressure overload heart failure in male mice
22.
https://doi.org/10.1002/adfm.202408767 （2024.9）
Inhalation of Bioorthogonal Gene-Editable Spiky-Pollen Reprograms Tumor-Associated Macrophages for Lung Cancer Immunotherapy
23.
https://onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202311537（2024.1）
ACE2 Receptor-Targeted Inhaled Nanoemulsions Inhibit SARS-CoV-2 and Attenuate Inflammatory Responses
24.
https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-024-05655-0 （2024.10）
Albendazole ameliorates aerobic glycolysis in myofibroblasts to reverse pulmonary fibrosis
25.
https://pubs.acs.org/doi/10.1021/acsnano.4c15130 (2025.1)
Inhalable siRNA Targeting IL-11 Nanoparticles Significantly Inhibit Bleomycin-Induced Pulmonary Fibrosis
26.
https://www.sciencedirect.com/science/article/pii/S1818087623000429 (2023.5)
Corrugated surface microparticles with chitosan and levofloxacin for improved aerodynamic performance
27.
https://doi.org/10.1002/adma.202404264 (2024.6)
Chemically Programmed Hydrogels for Spatiotemporal Modulation of the Cardiac Pathological Microenvironment
28.
https://doi.org/10.1007/s11426-024-2600-1 （2025.4）
Construct nucleic acid delivery carriers with excellent antibacterial capabilities for the treatment of bacterial MRSA-induced lung inflammation
29.
https://www.sciencedirect.com/science/article/pii/S2090123224002546 （May 2025）
Kynurenine acts as a signaling molecule to attenuate pulmonary fibrosis by enhancing the AHR-PTEN axis
Dry powder：
1.
https://doi.org/10.1016/j.powtec.2022.117679
Co-achievement of enhanced absorption and elongated retention of insoluble drug in lungs for inhalation therapy of pulmonary fibrosis
2.
https://www.sciencedirect.com/science/article/pii/S0168365923002791 (2023.6)
Neutralisation of SARS-CoV-2 by monoclonal antibody through dual targeting powder formulation
3.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786194/（2022.12）
Development and Pharmacokinetics of a Novel Acetylsalicylic Acid Dry Powder for Pulmonary Administration
4.
https://www.sciencedirect.com/science/article/pii/S1818087623000429 (2023.5)
Corrugated surface microparticles with chitosan and levofloxacin for improved aerodynamic performance
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